Organotin(IV) Carboxylates of Substituted α-Cinnamic Acid, RnSn(OCOC(R2)=CHR1)4 - n: Synthesis, Spectroscopic Characterization and Biological Evaluation

Di- and triorganotin(IV) carboxylates, RnSn(OCOC(R-2)=CHR1)(4-n) (n = 2 and 3; R = Me, Et, n-Bu, Ph; R-1 = 3-CH3O-4-OHC6H3, R-2 = C6H5) were prepared by reacting the corresponding organotin(IV) chloride with the silver salt of the (E)-3-(4-hydroxy-3-methoxyphenyl)2- phenylpropenoic acid. The title compounds were investigated and characterized by elemental analysis, infrared (FT-IR), multinuclear (H-1, C-13, Sn-119) NMR, and mass spectrometry, and possible structures were proposed. The complexes and ligand acid (HL) have been evaluated in vitro against various bacteria and fungi. The results noticed during the biocidal activity screenings proved their in vitro biological potential. They were also tested for cytotoxicity. (C) 2015 Wiley Periodicals, Inc.