4.6 Review

Antiulcer Agents: From Plant Extracts to Phytochemicals in Healing Promotion

Journal

MOLECULES
Volume 23, Issue 7, Pages -

Publisher

MDPI
DOI: 10.3390/molecules23071751

Keywords

peptic ulcer; Helicobacter pylori; gastric cancer; bioactive phytochemicals; herbal remedies; traditional healing systems

Funding

  1. Vicerrectoria de Investigacion y Desarrollo from University of Concepcion, Chile [216.073.031-1.0IN, 217.073.033-1.0]

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In this narrative review, we have comprehensively reviewed the plant sources used as antiulcer agents. From traditional uses as herbal remedies, we have moved on to preclinical evidence, critically discussing the in vitro and in vivo studies focusing on plant extracts and even isolated phytochemicals with antiulcerogenic potential. A particular emphasis was also paid to Helicobacter pylori activity, with emphasis on involved mechanisms of action. Lastly, the issue of safety profile of these plant products has also been addressed.

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