Journal
CHINESE HERBAL MEDICINES
Volume 5, Issue 4, Pages 313-316Publisher
ELSEVIER SINGAPORE PTE LTD
DOI: 10.1016/S1674-6384(13)60047-7
Keywords
Compositae; Eclipta prostrata; glycoside; isoflavonoid saponins; 7-O-methylorobol-4'-O-beta-D-glucopyranoside
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Funding
- Program for New Century Excellent Talents in University [NCET-10-0958]
- Important Drug Development Fund
- Ministry of Science and Technology of China [2011ZX09307-002-01]
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Objective To study the constituents in the dried aerial parts of Eclipta prostrata. Methods The constituents were isolated and purified by column chromatography and their structures were elucidated by spectroscopic methods (1D, 2D NMR, UV, IR, and HRESI-TOF-MS) and chemical analyses. Results Eight compounds were isolated and identified as 7-O-methylorobol-4'-O-beta-D-glucopyranoside (1), 3'-hydroxybiochanin A (2), echinocystic acid 28-O-beta-D-glucopyranoside (3), ecliptasaponin A (4), eclalbasaponin I (5), eclalbasaponin IV (6), echinocystic acid (7), and 3-oxo-16 alpha-hydroxy-olean-12-en-28-oic acid (8). Conclusion Compound 1 is a new compound and compound 3 is obtained from this genus for the first time.
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