Journal
MOLECULES
Volume 23, Issue 4, Pages -Publisher
MDPI
DOI: 10.3390/molecules23040935
Keywords
diterpenoids; Euphorbia fischeriana Steud; bioactivity
Funding
- National Natural Science Foundation of China [81573660]
- Intramural Research Program of the Qiqihar Medical University [QY2016Z-01]
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Diterpenoids are the focus of natural product drug discovery because of their great structural diversity and pronounced biological activities. Euphorbia fischeriana Steud is a Chinese traditional medicinal herb for curing edema, ascites, and cancer. This plant contains rich diterpenoids. Based on the carbon skeleton and substituents, it can be classified into thirteen subtypes: ent-abietane, daphnane, tigliane, ingenane, ent-atisane, ent-rosane, ent-kaurene, ent-kaurane, secotigliane, lathyrane, ent-pimarene, isopimarene and dimeric. In this paper, we reviewed the chemical structures and biological activities of 90 diterpenoids isolated from this medicinal herb. We hope that this work can serve as a reference for further research of these diterpenoids and lay the foundation for drug discovery.
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