4.7 Review

The roles of TGFβ in the tumour microenvironment

Journal

NATURE REVIEWS CANCER
Volume 13, Issue 11, Pages 788-799

Publisher

NATURE PORTFOLIO
DOI: 10.1038/nrc3603

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Funding

  1. US National Institutes of Health (NIH) [CA085492, CA102162]

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The influence of the microenvironment on tumour progression is becoming clearer. In this Review we address the role of an essential signalling pathway, that of transforming growth factor-beta, in the regulation of components of the tumour microenvironment and how this contributes to tumour progression.

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