4.8 Review

The role of adult hippocampal neurogenesis in brain health and disease

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Hippocampal bone morphogenetic protein signaling mediates behavioral effects of antidepressant treatment

S. M. Brooker et al.

MOLECULAR PSYCHIATRY (2017)

Editorial Material Neurosciences

Hippocampal neurogenesis and pattern separation: A meta-analysis of behavioral data

Thiago F. A. Franca et al.

HIPPOCAMPUS (2017)

Article Multidisciplinary Sciences

Human umbilical cord plasma proteins revitalize hippocampal function in aged mice

Joseph M. Castellano et al.

NATURE (2017)

Article Biochemical Research Methods

Sequencing thousands of single-cell genomes with combinatorial indexing

Sarah A. Vitak et al.

NATURE METHODS (2017)

Review Psychology, Experimental

Neurogenesis and pattern separation: time for a divorce

Suzanna Becker

WILEY INTERDISCIPLINARY REVIEWS-COGNITIVE SCIENCE (2017)

Article Behavioral Sciences

Age-Related Impairment on a Forced-Choice Version of the Mnemonic Similarity Task

Derek J. Huffman et al.

BEHAVIORAL NEUROSCIENCE (2017)

Review Neurosciences

Adult Hippocampal Neurogenesis, Fear Generalization, and Stress

Antoine Besnard et al.

NEUROPSYCHOPHARMACOLOGY (2016)

Article Biochemistry & Molecular Biology

Long Neural Genes Harbor Recurrent DNA Break Clusters in Neural Stem/Progenitor Cells

Pei-Chi Wei et al.

Article Cell & Tissue Engineering

Multipotency of Adult Hippocampal NSCs In Vivo Is Restricted by Drosha/NFIB

Chiara Rolando et al.

CELL STEM CELL (2016)

Article Biochemistry & Molecular Biology

Assessment of megabase-scale somatic copy number variation using single-cell sequencing

Kristin A. Knouse et al.

GENOME RESEARCH (2016)

Article Biochemistry & Molecular Biology

Neuropilin 2 Signaling Is Involved in Cell Positioning of Adult-born Neurons through Glycogen Synthase Kinase-3β (GSK3β)

Teclise Ng et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2016)

Article Neurosciences

In vivo imaging of dendritic pruning in dentate granule cells

J. Tiago Goncalves et al.

NATURE NEUROSCIENCE (2016)

Article Neurosciences

Running rewires the neuronal network of adult-born dentate granule cells

Carmen Vivar et al.

NEUROIMAGE (2016)

Article Clinical Neurology

Human adult neurogenesis across the ages: An immunohistochemical study

C. V. Dennis et al.

NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2016)

Article Multidisciplinary Sciences

Transcription-associated processes cause DNA double-strand breaks and translocations in neural stem/progenitor cells

Bjoern Schwer et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Article Multidisciplinary Sciences

Ventral CA1 neurons store social memory

Teruhiro Okuyama et al.

SCIENCE (2016)

Article Cell Biology

Computational Modeling of Adult Neurogenesis

James B. Aimone

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2016)

Article Neurosciences

The Wnt Adaptor Protein ATP6AP2 Regulates Multiple Stages of Adult Hippocampal Neurogenesis

Simon T. Schafer et al.

JOURNAL OF NEUROSCIENCE (2015)

Article Neurosciences

Experience-Dependent Regulation of Dentate Gyrus Excitability by Adult-Born Granule Cells

Eun Hye Park et al.

JOURNAL OF NEUROSCIENCE (2015)

Article Biochemistry & Molecular Biology

beta 2-microglobulin is a systemic pro-aging factor that impairs cognitive function and neurogenesis

Lucas K. Smith et al.

NATURE MEDICINE (2015)

Article Multidisciplinary Sciences

SOX2 primes the epigenetic landscape in neural precursors enabling proper gene activation during hippocampal neurogenesis

Alejandro Amador-Arjona et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Multidisciplinary Sciences

Adult hippocampal neural stem and progenitor cells regulate the neurogenic niche by secreting VEGF

Elizabeth D. Kirby et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Multidisciplinary Sciences

Somatic mutation in single human neurons tracks developmental and transcriptional history

Michael A. Lodato et al.

SCIENCE (2015)

Article Cell & Tissue Engineering

Age-Associated Increase in BMP Signaling Inhibits Hippocampal Neurogenesis

Hanadie Yousef et al.

STEM CELLS (2015)

Article Neurosciences

Enrichment Rescues Contextual Discrimination Deficit Associated With Immediate Shock

Gregory D. Clemenson et al.

HIPPOCAMPUS (2015)

Article Developmental Biology

GABA suppresses neurogenesis in the adult hippocampus through GABAB receptors

Claudio Giachino et al.

DEVELOPMENT (2014)

Article Neurosciences

Dissecting Integrin-Dependent Regulation of Neural Stem Cell Proliferation in the Adult Brain

Cristina Porcheri et al.

JOURNAL OF NEUROSCIENCE (2014)

Article Biochemistry & Molecular Biology

Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice

Saul A. Villeda et al.

NATURE MEDICINE (2014)

Article Multidisciplinary Sciences

Single cell sequencing reveals low levels of aneuploidy across mammalian tissues

Kristin A. Knouse et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Multidisciplinary Sciences

Hippocampal Neurogenesis Regulates Forgetting During Adulthood and Infancy

Katherine G. Akers et al.

SCIENCE (2014)

Article Cell & Tissue Engineering

Modeling Hippocampal Neurogenesis Using Human Pluripotent Stem Cells

Diana Xuan Yu et al.

STEM CELL REPORTS (2014)

Article Biochemistry & Molecular Biology

Dynamics of Hippocampal Neurogenesis in Adult Humans

Kirsty L. Spalding et al.

Article Cell & Tissue Engineering

Tet1 Regulates Adult Hippocampal Neurogenesis and Cognition

Run-Rui Zhang et al.

CELL STEM CELL (2013)

Article Neurosciences

GABA Depolarization Is Required for Experience-Dependent Synapse Unsilencing in Adult-Born Neurons

Jessica H. Chancey et al.

JOURNAL OF NEUROSCIENCE (2013)

Article Neurosciences

Distinct Determinants of Sparse Activation during Granule Cell Maturation

Cristina V. Dieni et al.

JOURNAL OF NEUROSCIENCE (2013)

Article Neurosciences

Glucocorticoids Orchestrate Divergent Effects on Mood through Adult Neurogenesis

Michael L. Lehmann et al.

JOURNAL OF NEUROSCIENCE (2013)

Article Neurosciences

Nuclear Lamins in the Brain - New Insights into Function and Regulation

Hea-Jin Jung et al.

MOLECULAR NEUROBIOLOGY (2013)

Article Multidisciplinary Sciences

Retrograde monosynaptic tracing reveals the temporal evolution of inputs onto new neurons in the adult dentate gyrus and olfactory bulb

Aditi Deshpande et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Neurosciences

Adult neurogenesis modifies excitability of the dentate gyrus

Taruna Ikrar et al.

FRONTIERS IN NEURAL CIRCUITS (2013)

Article Behavioral Sciences

The Role of Adult Hippocampal Neurogenesis in Reducing Interference

Paul Luu et al.

BEHAVIORAL NEUROSCIENCE (2012)

Article Neurosciences

Adult-born neurons are necessary for extended contextual discrimination

Sophie Tronel et al.

HIPPOCAMPUS (2012)

Article Neurosciences

Adult-born hippocampal neurons promote cognitive flexibility in mice

Nesha S. Burghardt et al.

HIPPOCAMPUS (2012)

Article Biochemistry & Molecular Biology

SRY-box-containing Gene 2 Regulation of Nuclear Receptor Tailless (Tlx) Transcription in Adult Neural Stem Cells

Koji Shimozaki et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Article Biochemistry & Molecular Biology

Inducible and Conditional Deletion of Extracellular Signal-regulated Kinase 5 Disrupts Adult Hippocampal Neurogenesis

Yung-Wei Pan et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Article Neurosciences

Role of α-Synuclein in Adult Neurogenesis and Neuronal Maturation in the Dentate Gyrus

Beate Winner et al.

JOURNAL OF NEUROSCIENCE (2012)

Article Neurosciences

Astrocytes regulate adult hippocampal neurogenesis through ephrin-B signaling

Randolph S. Ashton et al.

NATURE NEUROSCIENCE (2012)

Article Multidisciplinary Sciences

Unique Processing During a Period of High Excitation/Inhibition Balance in Adult-Born Neurons

Antonia Marin-Burgin et al.

SCIENCE (2012)

Article Multidisciplinary Sciences

Suppression of adult neurogenesis impairs population coding of similar contexts in hippocampal CA3 region

Yosuke Niibori et al.

NATURE COMMUNICATIONS (2012)

Article Multidisciplinary Sciences

Monosynaptic inputs to new neurons in the dentate gyrus

Carmen Vivar et al.

NATURE COMMUNICATIONS (2012)

Article Neurosciences

The Timing for Neuronal Maturation in the Adult Hippocampus Is Modulated by Local Network Activity

Veronica C. Piatti et al.

JOURNAL OF NEUROSCIENCE (2011)

Article Biochemistry & Molecular Biology

Antidepressants increase human hippocampal neurogenesis by activating the glucocorticoid receptor

C. Anacker et al.

MOLECULAR PSYCHIATRY (2011)

Article Biochemistry & Molecular Biology

Antidepressants recruit new neurons to improve stress response regulation

A. Surget et al.

MOLECULAR PSYCHIATRY (2011)

Article Multidisciplinary Sciences

The ageing systemic milieu negatively regulates neurogenesis and cognitive function

Saul A. Villeda et al.

NATURE (2011)

Article Multidisciplinary Sciences

Adult hippocampal neurogenesis buffers stress responses and depressive behaviour

Jason S. Snyder et al.

NATURE (2011)

Article Multidisciplinary Sciences

Age-related memory deficits linked to circuit-specific disruptions in the hippocampus

Michael A. Yassa et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Multidisciplinary Sciences

Prospero-related homeobox 1 gene (Prox1) is regulated by canonical Wnt signaling and has a stage-specific role in adult hippocampal neurogenesis

Oezlem Karalay et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Neurosciences

Transient elevation of adult hippocampal neurogenesis after dopamine depletion

June-Hee Park et al.

EXPERIMENTAL NEUROLOGY (2010)

Article Cell Biology

Cross talk between microRNA and epigenetic regulation in adult neurogenesis

Keith E. Szulwach et al.

JOURNAL OF CELL BIOLOGY (2010)

Article Neurosciences

Notch1 Is Required for Maintenance of the Reservoir of Adult Hippocampal Stem Cells

Jessica L. Ables et al.

JOURNAL OF NEUROSCIENCE (2010)

Article Multidisciplinary Sciences

L1 retrotransposition in neurons is modulated by MeCP2

Alysson R. Muotri et al.

NATURE (2010)

Article Neurosciences

The specific role of histone deacetylase 2 in adult neurogenesis

Melanie Jawerka et al.

NEURON GLIA BIOLOGY (2010)

Article Multidisciplinary Sciences

microRNA-132 regulates dendritic growth and arborization of newborn neurons in the adult hippocampus

Stephen T. Magill et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Multidisciplinary Sciences

Running enhances spatial pattern separation in mice

David J. Creer et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Biochemistry & Molecular Biology

Adult Neurogenesis Modulates the Hippocampus-Dependent Period of Associative Fear Memory

Takashi Kitamura et al.

Article Cell & Tissue Engineering

FoxO3 Regulates Neural Stem Cell Homeostasis

Valerie M. Renault et al.

CELL STEM CELL (2009)

Article Biochemistry & Molecular Biology

Adult hippocampal neurogenesis is involved in anxiety-related behaviors

J-M Revest et al.

MOLECULAR PSYCHIATRY (2009)

Article Neurosciences

Wnt-mediated activation of NeuroD1 and retro-elements during adult neurogenesis

Tomoko Kuwabara et al.

NATURE NEUROSCIENCE (2009)

Article Neurosciences

Antidepressants increase neural progenitor cells in the human hippocampus

Maura Boldrini et al.

NEUROPSYCHOPHARMACOLOGY (2009)

Article Multidisciplinary Sciences

Reliable Activation of Immature Neurons in the Adult Hippocampus

Lucas A. Mongiat et al.

PLOS ONE (2009)

Article Multidisciplinary Sciences

A Functional Role for Adult Hippocampal Neurogenesis in Spatial Pattern Separation

C. D. Clelland et al.

SCIENCE (2009)

Article Developmental Biology

Neurogenin 2 has an essential role in development of the dentate gyrus

Christophe Galichet et al.

DEVELOPMENT (2008)

Article Neurosciences

The effects of running and of inhibiting adult neurogenesis on learning and memory in rats

J. Martin Wojtowicz et al.

EUROPEAN JOURNAL OF NEUROSCIENCE (2008)

Article Biochemistry & Molecular Biology

Epigenetic regulation of the stem cell mitogen Fgf-2 by Mbd1 in adult neural stem/progenitor cells

Xuekun Li et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Neurosciences

Aneuploid mosaicism in the developing and adult cerebellar cortex

Jurjen W. Westra et al.

JOURNAL OF COMPARATIVE NEUROLOGY (2008)

Article Clinical Neurology

Failure of neuronal maturation in Alzheimer disease dentate gyrus

Bin Li et al.

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2008)

Article Neurosciences

Noggin expands neural stem cells in the adult hippocampus

Michael A. Bonaguidi et al.

JOURNAL OF NEUROSCIENCE (2008)

Article Neurosciences

Neurodegeneration and motor dysfunction in a conditional model of Parkinson's disease

Silke Nuber et al.

JOURNAL OF NEUROSCIENCE (2008)

Letter Biochemistry & Molecular Biology

Chronic fluoxetine treatment alters behavior, but not adult hippocampal neurogenesis, in BALB/cJ mice

G-J Huang et al.

MOLECULAR PSYCHIATRY (2008)

Article Multidisciplinary Sciences

A role for adult TLX-positive neural stem cells in learning and behaviour

Chun-Li Zhang et al.

NATURE (2008)

Article Neurosciences

Neurons born in the adult dentate gyrus form functional synapses with target cells

Nicolas Toni et al.

NATURE NEUROSCIENCE (2008)

Article Neurosciences

Directed differentiation of hippocampal stem/progenitor cells in the adult brain

Sebastian Jessberger et al.

NATURE NEUROSCIENCE (2008)

Article Multidisciplinary Sciences

Spatial Relational Memory Requires Hippocampal Adult Neurogenesis

David Dupret et al.

PLOS ONE (2008)

Article Multidisciplinary Sciences

Primary cilia regulate hippocampal neurogenesis by mediating sonic hedgehog signaling

Joshua J. Breunig et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Multidisciplinary Sciences

Development of hippocampal mossy fiber synaptic outputs by new neurons in the adult brain

Regina L. Faulkner et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Multidisciplinary Sciences

Magnetic resonance spectroscopy identifies neural progenitor cells in the live human brain

Louis N. Manganas et al.

SCIENCE (2007)

Article Neurosciences

Mecp2 deficiency leads to delayed maturation and altered gene expression in hippocampal neurons

Richard D. Smrt et al.

NEUROBIOLOGY OF DISEASE (2007)

Article Neurosciences

Antidepressant-induced neurogenesis in the hippocampus of adult nonhuman primates

Tarique D. Perera et al.

JOURNAL OF NEUROSCIENCE (2007)

Article Neurosciences

Reelin regulates neuronal progenitor migration in intact and epileptic hippocampus

Chao Gong et al.

JOURNAL OF NEUROSCIENCE (2007)

Article Multidisciplinary Sciences

Pattern separation in the dentate gyrus and CA3 of the hippocampus

Jill K. Leutgeb et al.

SCIENCE (2007)

Article Neurosciences

Synapse formation on neurons born in the adult hippocampus

Nicolas Toni et al.

NATURE NEUROSCIENCE (2007)

Article Multidisciplinary Sciences

Ablation of hippocampal neurogenesis impairs contextual fear conditioning and synaptic plasticity in the dentate gyrus

Michael D. Saxe et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Multidisciplinary Sciences

NMDA-receptor-mediated, cell-specific integration of new neurons in adult dentate gyrus

Ayumu Tashiro et al.

NATURE (2006)

Review Neurosciences

A computational theory of hippocampal function, and empirical tests of the theory

Edmund T. Rolls et al.

PROGRESS IN NEUROBIOLOGY (2006)

Article Neurosciences

Seizures accelerate functional integration of adult-generated granule cells

LS Overstreet-Wadiche et al.

JOURNAL OF NEUROSCIENCE (2006)

Article Biochemistry & Molecular Biology

Modulation of adult hippocampal neurogenesis by thyroid hormones:: implications in depressive-like behavior

A Montero-Pedrazuela et al.

MOLECULAR PSYCHIATRY (2006)

Article Neurosciences

Differential properties of adult rat and mouse brain-derived neural stem/progenitor cells

J Ray et al.

MOLECULAR AND CELLULAR NEUROSCIENCE (2006)

Article Neurosciences

Decreased adult hippocampal neurogenesis in the PDAPP mouse model of Alzheimer's disease

MH Donovan et al.

JOURNAL OF COMPARATIVE NEUROLOGY (2006)

Article Clinical Neurology

Aberrant seizure-induced neurogenesis in experimental temporal lobe epilepsy

JM Parent et al.

ANNALS OF NEUROLOGY (2006)

Article Neurosciences

GABAergic signaling to newborn neurons in dentate gyrus

LO Wadiche et al.

JOURNAL OF NEUROPHYSIOLOGY (2005)

Article Neurosciences

Neuronal differentiation in the adult hippocampus recapitulates embryonic development

MS Espósito et al.

JOURNAL OF NEUROSCIENCE (2005)

Article Multidisciplinary Sciences

Wnt signalling regulates adult hippocampal neurogenesis

DC Lie et al.

NATURE (2005)

Article Neurosciences

Exercise enhances learning and hippocampal neurogenesis in aged mice

H van Praag et al.

JOURNAL OF NEUROSCIENCE (2005)

Article Multidisciplinary Sciences

Somatic mosaicism in neuronal precursor cells mediated by L1 retrotransposition

AR Muotri et al.

NATURE (2005)

Article Geriatrics & Gerontology

Forebrain acetylcholine regulates adult hippocampal neurogenesis and learning

P Mohapel et al.

NEUROBIOLOGY OF AGING (2005)

Review Psychiatry

Lower hippocampal volume in patients suffering from depression: A meta-analysis

S Campbell et al.

AMERICAN JOURNAL OF PSYCHIATRY (2004)

Article Multidisciplinary Sciences

Increased hippocampal neurogenesis in Alzheimer's disease

KL Jin et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Neurosciences

Early life experience alters response of adult neurogenesis to stress

C Mirescu et al.

NATURE NEUROSCIENCE (2004)

Review Neurosciences

Decreased neurogenesis after cholinergic forebrain lesion in the adult rat

CM Cooper-Kuhn et al.

JOURNAL OF NEUROSCIENCE RESEARCH (2004)

Article Neurosciences

Dopamine depletion impairs precursor cell proliferation in Parkinson disease

GU Höglinger et al.

NATURE NEUROSCIENCE (2004)

Article Clinical Neurology

Human wild-type α-synuclein impairs neurogenesis

B Winner et al.

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2004)

Article Multidisciplinary Sciences

Enhanced synaptic plasticity in newly generated granule cells of the adult hippocampus

C Schmidt-Hieber et al.

NATURE (2004)

Article Multidisciplinary Sciences

Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants

L Santarelli et al.

SCIENCE (2003)

Article Multidisciplinary Sciences

Mice lacking methyl-CpG binding protein 1 have deficits in adult neurogenesis and hippocampal function

XY Zhao et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Neurosciences

Adult-born hippocampal neurons mature into activity-dependent responsiveness

S Jessberger et al.

EUROPEAN JOURNAL OF NEUROSCIENCE (2003)

Article Multidisciplinary Sciences

Chromosomal variation in neurons of the developing and adult mammalian nervous system

SK Rehen et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Article Multidisciplinary Sciences

Functional requirement for class I MHC in CNS development and plasticity

GS Huh et al.

SCIENCE (2000)

Article Multidisciplinary Sciences

Opiates inhibit neurogenesis in the adult rat hippocampus

AJ Eisch et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)