Journal
MOLECULAR BIOTECHNOLOGY
Volume 60, Issue 7, Pages 506-532Publisher
HUMANA PRESS INC
DOI: 10.1007/s12033-018-0084-5
Keywords
Scaffolds; PCL; Composite; Stem cells and tissue engineering
Funding
- Science and Engineering Board (SERB), Department of Science and Technology, Government of India, New Delhi under the program National Postdoctoral Fellowship (DST) [PDF/2016/000467]
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Biomaterial-based scaffolds are important cues in tissue engineering (TE) applications. Recent advances in TE have led to the development of suitable scaffold architecture for various tissue defects. In this narrative review on polycaprolactone (PCL), we have discussed in detail about the synthesis of PCL, various properties and most recent advances of using PCL and PCL blended with either natural or synthetic polymers and ceramic materials for TE applications. Further, various forms of PCL scaffolds such as porous, films and fibrous have been discussed along with the stem cells and their sources employed in various tissue repair strategies. Overall, the present review affords an insight into the properties and applications of PCL in various tissue engineering applications.
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