4.6 Article

Genome sequencing and functional characterization of the nonpathogenic Klebsiella pneumoniae KpGe bacteria

Journal

MICROBES AND INFECTION
Volume 20, Issue 5, Pages 293-301

Publisher

ELSEVIER
DOI: 10.1016/j.micinf.2018.04.001

Keywords

Dictyostelium discoideum; Klebsiella pneumoniae; Host-pathogen interactions; Non-pathogenic strain

Funding

  1. Swiss National Science Foundation [31003A_153326]
  2. Institute of Microbiology, Lausanne
  3. Swiss National Science Foundation (SNF) [31003A_153326] Funding Source: Swiss National Science Foundation (SNF)

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Klebsiella pneumoniae is an extensively studied human pathogen responsible for a wide variety of infections. Dictyostelium discoideum is a model host organism employed to study many facets of the complex interactions between phagocytic cells and bacteria. Historically, a non-pathogenic strain of K. pneumoniae has been used to feed Dictyostelium amoebae, and more recently to study cellular mechanisms involved in bacterial recognition, ingestion and killing. Here we provide the full genome sequence and functional characterization of this non-pathogenic KpGe strain. (C) 2018 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.

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