Hybrid nanocomposites made with cellulose and ZnO nanoparticles and its biosensing application

This paper reports a flexible and disposable ZnO blended cellulose hybrid nanocomposites (Cellulose/ZnO hybrid) film and its feasibility for a resistive glucose biosensor. Cellulose/ZnO hybrid film was fabricated by simply blending ZnO nanoparticles with cellulose solution prepared by dissolving cotton pulp with LiCl/DMAc solvent. Cellulose/ZnO hybrid film was cured in isopropyl alcohol and water mixture and free standing film was obtained. For biosensor application, the enzyme glucose oxidase was immobilized into the Cellulose/ZnO hybrid film by physical adsorption method. The enzyme activity of the glucose biosensor increases as the ZnO weight ratio increases linearly in the range of 1-12mM.