Journal
HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA
Volume 29, Issue 2, Pages 237-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.hoc.2014.10.011
Keywords
Urothelial carcinoma; Variant histology; Micropapillary bladder cancer; Radical cystectomy; Chemotherapy; Treatment guidelines
Categories
Funding
- Photocure Advisory Board
- Bioniche Consultant
- Sanofi Advisory Board
- Merck Advisory Board
- Abbott Molecular Consultant
- Theralese Consultant
- Heat Biologics Research Funding
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At present, radical cystectomy is a mainstay in the management of all bladder cancers, whether of conventional urothelial histology or variant. However, in the case of some variants, it is clearly not enough and multi-modal therapy is an imperative. In other cases, systemic therapy might be ineffective or even detrimental if it leads to delay in surgery (ie, squamous cell carcinoma). Thus, identification of variant histology is a critical part of bladder cancer staging because such histology may require appropriately tailored therapy.
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