Umpolung reactions at the α-carbon position of carbonyl compounds

Umpolung chemistry has been a focus of research in organic synthesis because of its usefulness and unusual reactivity. Above all, umpolung of enamine properties enables the formation of highly substituted carbon-carbon bonds and the installation of aryl groups which is difficult to achieve using normal enolate chemistry. This short review describes reports of carbon-carbon bond formation using umpolung reactions of enol and enamine derivatives.