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Association between obesity with disease-free survival and overall survival in triple-negative breast cancer: A meta-analysis

Journal

MEDICINE
Volume 97, Issue 19, Pages -

Publisher

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/MD.0000000000010719

Keywords

disease-free survival; meta-analysis; obesity; overall survival; triple-negative breast cancer

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Objective:To investigate the relationship between obesity and disease-free survival (DFS) and overall survival (OS) of triple-negative breast cancer.Methods:Citations were searched in PubMed, Cochrane Library, and Web of Science. Random effect model meta-analysis was conducted by using Revman software version 5.0, and publication bias was evaluated by creating Egger regression with STATA software version 12.Results:Nine studies (4412 patients) were included for DFS meta-analysis, 8 studies (4392 patients) include for OS meta-analysis. There were no statistical significances between obesity with DFS (P=.60) and OS (P=.71) in triple-negative breast cancer (TNBC) patients.Conclusion:Obesity has no impact on DFS and OS in patients with TNBC.

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