4.6 Article

Quantitative transmission ultrasound tomography: Imaging and performance characteristics

Journal

MEDICAL PHYSICS
Volume 45, Issue 7, Pages 3063-3075

Publisher

WILEY
DOI: 10.1002/mp.12957

Keywords

imaging performance; inverse scattering; QT ultrasound; transmission ultrasound; ultrasound tomography

Funding

  1. National Institutes of Health [R01 CA138536]

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PurposeQuantitative Transmission (QT) ultrasound has shown promise as a breast imaging modality. This study characterizes the performance of the latest generation of QT ultrasound scanners: QT Scanner 2000. MethodsThe scanner consists of a 2048-element ultrasound receiver array for transmission imaging and three transceivers for reflection imaging. Custom fabricated phantoms were used to quantify the imaging performance parameters. The specific performance parameters that have been characterized are spatial resolution (as point spread function), linear measurement accuracy, contrast to noise ratio, and image uniformity, in both transmission and reflection imaging modalities. ResultsThe intrinsic in-plane resolution was measured to be better than 1.5mm and 1.0mm for transmission and reflection modalities respectively. The linear measurement accuracy was measured to be, on average, approximately 1% for both the modalities. Speed of sound image uniformity and measurement accuracy were calculated to be 99.5% and <0.2% respectively. Contrast to noise ratio (CNR) measurements vary as a function of object size. ConclusionsThe results show an improvement in the imaging performance of the system in comparison to earlier ultrasound tomography systems, which are applicable to clinical applications of the system, such as breast imaging.

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