4.5 Article

Classification of micro-calcification in mammograms using scalable linear Fisher discriminant analysis

Journal

MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING
Volume 56, Issue 8, Pages 1475-1485

Publisher

SPRINGER HEIDELBERG
DOI: 10.1007/s11517-017-1774-z

Keywords

Micro-calcification; Classification; Fisher discriminant analysis; Principal component analysis; Computer aided detection; Dimensionality reduction

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Breast cancer is one of the major causes of death in women. Computer Aided Diagnosis (CAD) systems are being developed to assist radiologists in early diagnosis. Micro-calcifications can be an early symptom of breast cancer. Besides detection, classification of micro-calcification as benign or malignant is essential in a complete CAD system. We have developed a novel method for the classification of benign and malignant micro-calcification using an improved Fisher Linear Discriminant Analysis (LDA) approach for the linear transformation of segmented micro-calcification data in combination with a Support Vector Machine (SVM) variant to classify between the two classes. The results indicate an average accuracy equal to 96% which is comparable to state-of-the art methods in the literature.

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