Fruit-mediated synthesis of silver nanoparticles using Vitis vinifera and evaluation of their antimicrobial efficacy

Nanobiotechnology is a rapidly growing scientific field of producing and constructing devices utilizing nanosized particles of about nanometer scale level (1 to 100 nm). Nowadays, nanoparticles have potential effects in life sciences and human health care applications. Among the nanoparticles, silver nanoparticles are playing a major role in the field of biomedical nanotechnology and nanomedicine. Silver is a naturally occurring precious metal, most often as a mineral ore in association with other elements. Silver nanoparticle has a natural antimicrobial effect against many pathogens such as bacteria, fungus, viruses, and yeast. In this present study, the silver nanoparticle is produced using Vitis vinifera fruit extract, and the purified nanoparticles will be used as an antibacterial agent against Bacillus subtilis and Klebsiella planticola. This green chemistry for the biosynthesis of silver nanoparticles has several advantages such as cost-effectiveness and compatibility for biomedical and pharmaceutical applications as well as for large-scale commercial production. Apart from this, it is an eco-friendly process, and compared with microorganisms, plant extract biorecovery unit has an added benefit of ease handling.