4.6 Article

Spatial-temporal basic reproduction number and dynamics for a dengue disease diffusion model

Journal

MATHEMATICAL METHODS IN THE APPLIED SCIENCES
Volume 41, Issue 14, Pages 5388-5403

Publisher

WILEY
DOI: 10.1002/mma.5085

Keywords

dengue disease; free boundary; reaction-diffusion system; spatial-temporal basic reproduction number; spreading and vanishing

Funding

  1. National Natural Science Foundation of China [11771407]
  2. Innovative Research Team of Science and Technology in Henan Province [17IRTSTHN007]
  3. National Key R&D Program of China [2017YFB0702500]

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A reaction-diffusion system with free boundary is proposed to describe the transmission of the dengue disease from mosquitoes to humans. In addition to the classical basic reproduction number R-0, the spatial-temporal basic reproduction number R0F(t) is introduced to determine the persistence and eradication of the disease. Some sufficient conditions for the disease vanishing or spreading are obtained. The disease will go extinct under one of the conditions: the classical basic reproduction number R(0)1 and the spatial-temporal basic reproduction number R0 spread of the disease in the whole area is possible if for some t0. Numerical simulations are also given to illustrate the theoretical results.

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