Journal
MATHEMATICAL BIOSCIENCES
Volume 301, Issue -, Pages 147-158Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.mbs.2018.05.007
Keywords
Stem cells; Biological processes; Tissue development; Three-dimensional scaffolds; Phenomenological modeling
Categories
Funding
- CAPES (Coordination for the Improvement of Higher Education Personnel)
- National Council for Scientific and Technological Development (CNPq)
- FINEP (Financing Agency for Studies and Projects)
- Stem Cell Research Institute
Ask authors/readers for more resources
A potential alternative for tissue transplants is tissue engineering, in which the interaction of cells and biomaterials can be optimized. Tissue development in vitro depends on the complex interaction of several biological processes such as extracellular matrix synthesis, vascularization and cell proliferation, adhesion, migration, death, and differentiation. The complexity of an individual phenomenon or of the combination of these processes can be studied with phenomenological modeling techniques. This work reviews the main biological phenomena in tissue development and their mathematical modeling, focusing on mesenchymal stem cell growth in three-dimensional scaffolds.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available