Journal
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
Volume 90, Issue -, Pages 713-727Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.msec.2018.03.002
Keywords
Dendrimers; Biodegradable; Drug delivery
Categories
Funding
- NSFC [21474115, 51573195, 81630056, 21674120]
Ask authors/readers for more resources
Dendrimers, as a type of artificial polymers with unique structural features, have been extensively explored for their applications in biomedical fields, especially in drug delivery. However, one important concern about the most commonly used dendrimers exists - the nondegradability, which may cause side effects induced by the accumulation of synthetic polymers in cells or tissues. Therefore, biodegradable dendrimers incorporating biodegradability with merits of dendrimers such as well-defined architectures, copious internal cavities and surface functionalities, are much more promising for developing novel nontoxic drug carriers. Herein, we review the recent advances in design and synthesis of biodegradable dendrimers, as well as their applications in fabricating drug delivery systems, with the aim to provide researchers in the related fields a good understanding of biodegradable dendrimers for drug delivery.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available