Novel gellan gum incorporated TiO2 nanotubes film for skin tissue engineering

Novel gellan gum incorporated TiO2 nanotubes (GG+TiO2-NT) film was successfully fabricated using solvent casting method for skin tissue engineering. The physicochemical properties of the film was investigated by FTIR, XRD and SEM. FTIR studies show the existence of interactions between TiO2 nanotubes and GG polymer matrix. XRD analysis revealed that the film was in amorphous state and the presence of TiO2 nanotubes on the surface of film was proved by SEM images. Cell proliferation studies demonstrated that, no sign of toxicity and the number of cells were found to be increased, thus exhibiting an ideal characteristic in skin tissue engineering applications. (C) 2018 Elsevier B.V. All rights reserved.