4.1 Article

Dianhydrohexitols: new tools for organocatalysis. Application in enantioselective Friedel-Crafts alkylation of indoles with nitroalkenes

Journal

ARKIVOC
Volume -, Issue -, Pages 227-244

Publisher

ARKAT USA INC
DOI: 10.3998/ark.5550190.0014.318

Keywords

Organocatalysis; biomass; asymmetric catalysis; isomannide; isoidide; thiourea

Funding

  1. Region Pays de la Loire
  2. CNRS
  3. Ministere de l'Enseignement Superieur et de la Recherche

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A series of hydrogen bonding organocatalysts was synthesized from dianhydrohexitol and was used for the first time in organocatalysis for Friedel-Crafts alkylation of indoles with nitroalkenes. Moderate yields and enantioselectivities were achieved.

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