ANATOLIA: NMR software for spectral analysis of total lineshape

In this paper we present a new fast and free open-source software package ANATOLIA for the total lineshape analysis of NMR spectra. It performs fitting of experimental 1D NMR spectra based on quantum mechanical formalism. The program serves for the determination of J-coupling constants and elucidation of complicated multiplet structures including strongly coupled systems. The program utilizes the Lorentzian broadening approach for local minima suppression. It is developed in the C++ language for standard personal computers. ANATOLIA is adapted to work with the Bruker NMR spectral format and could be conveniently integrated into the TopSpin software package. This tutorial contains a program description, 2 demonstration examples, and general recommendations for NMR spectra analysis.