Solubility improvement of hesperetin by using different octenyl succinic anhydride modified starches

To increase the solubility of hesperetin, four different octenyl succinic anhydride modified starches (OSAS) were prepared from corn, wheat, potato, and sweet potato starches and then complexed with hesperetin. Results showed that corn OSAS was the best among the four OSASs in improving the hesperetin solubility. The solubilization efficiency of hesperetin was increased by 9.87 times when it was complexed with corn OSAS at 44 g/L mass concentration and degree of substitution (DS) at 0.0158 by agitation (1600 r/min, 40 degrees C) for 4 h under native pH. Compared with the physical mixture of OSAS and hesperetin, the inclusion of their complex was confirmed by FT-IR, XRD and DSC. These results would have provided some basic understandings on the interactions between hesperetin and OSAS on solubility enhancement.