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DEVELOPMENTAL CELL (2008)
Detection of altered global DNA methylation in coronary artery disease patients
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DNA methylation in ES cells requires the lysine methyltransferase G9a but not its catalytic activity
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EMBO JOURNAL (2008)
G9a/GLP complexes independently mediate H3K9 and DNA methylation to silence transcription
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EMBO JOURNAL (2008)
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FEBS LETTERS (2008)
Genome-wide profiling of PPARγ:RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis
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GENES & DEVELOPMENT (2008)
Transgenic overexpression of Hdac3 in the heart produces increased postnatal cardiac myocyte proliferation but does not induce hypertrophy
Chinmay M. Trivedi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
An FHL1-containing complex within the cardiomyocyte sarcomere mediates hypertrophic biomechanical stress responses in mice
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JOURNAL OF CLINICAL INVESTIGATION (2008)
Maintenance of cardiac energy by histone deacetylase 3 metabolism in mice
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JOURNAL OF CLINICAL INVESTIGATION (2008)
DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells
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MOLECULAR AND CELLULAR BIOLOGY (2008)
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MOLECULAR AND CELLULAR BIOLOGY (2008)
Mice lacking histone deacetylase 6 have hyperacetylated tubulin but are viable and develop normally
Yu Zhang et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Kcnq1ot1 Antisense Noncoding RNA Mediates Lineage-Specific Transcriptional Silencing through Chromatin-Level Regulation
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MOLECULAR CELL (2008)
Evaluation of the flanking nucleotide sequences of sarcomeric hypertrophic cardiomyopathy substitution mutations
Kathryn M. Meurs et al.
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2008)
Tackling heart failure in the twenty-first century
James O. Mudd et al.
NATURE (2008)
Epigenetic events in mammalian germ-cell development: reprogramming and beyond
Hiroyuki Sasaki et al.
NATURE REVIEWS GENETICS (2008)
DNA methylation landscapes: provocative insights from epigenomics
Miho M. Suzuki et al.
NATURE REVIEWS GENETICS (2008)
De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes
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NATURE STRUCTURAL & MOLECULAR BIOLOGY (2008)
Molecular origins of cancer: Epigenetics in cancer
Manel Esteller
NEW ENGLAND JOURNAL OF MEDICINE (2008)
The eukaryotic genome as an RNA machine
Paulo P. Amaral et al.
SCIENCE (2008)
Mammalian DNA methyltransferases: A structural perspective
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STRUCTURE (2008)
The Histone H3K79 Methyltransferase Dot1L Is Essential for Mammalian Development and Heterochromatin Structure
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PLOS GENETICS (2008)
Susceptibility to coronary artery disease and diabetes is encoded by distinct, tightly linked SNPs in the ANRIL locus on chromosome 9p
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HUMAN MOLECULAR GENETICS (2008)
Mammalian sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation
David B. Lombard et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
SIRT1 transgenic mice show phenotypes resembling calorie restriction
Laura Bordone et al.
AGING CELL (2007)
JMJD6 is a histone arginine demethylase
Bingsheng Chang et al.
SCIENCE (2007)
Genome-wide profiling reveals a class of normally methylated CpG island promoters
Lanlan Shen et al.
PLOS GENETICS (2007)
A microduplication of CBP in a patient with mental retardation and a congenital heart defect
Bernard Thienpont et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2007)
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ONCOGENE (2007)
Chemistry of acetyl transfer by histone modifying enzymes: structure, mechanism and implications for effector design
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ONCOGENE (2007)
Distinct GCN5/PCAF-containing complexes function as co-activators and are involved in transcription factor and global histone acetylation
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ONCOGENE (2007)
Sirtuin 2 inhibitors rescue α-synuclein-mediated toxicity in models of Parkinson's disease
Tiago Fleming Outeiro et al.
SCIENCE (2007)
Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility
Rusty L. Montgomery et al.
GENES & DEVELOPMENT (2007)
RNA maps reveal new RNA classes and a possible function for pervasive transcription
Philipp Kapranov et al.
SCIENCE (2007)
A common allele on chromosome 9 associated with coronary heart disease
Ruth McPherson et al.
SCIENCE (2007)
Phenotypic plasticity and the epigenetics of human disease
Andrew P. Feinberg
NATURE (2007)
Stability and flexibility of epigenetic gene regulation in mammalian development
Wolf Reik
NATURE (2007)
High-resolution profiling of histone methylations in the human genome
Artern Barski et al.
CELL (2007)
Sensitive ChIP-DSL technology reveals an extensive estrogen receptor α-binding program on human gene promoters
Young-Soo Kwon et al.
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Stefan Neubauer
NEW ENGLAND JOURNAL OF MEDICINE (2007)
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Tony Kouzarides
CELL (2007)
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Multiple modes of interaction between the methylated DNA binding protein MeCP2 and chromatin
Tatiana Nikitina et al.
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Methylation of lysine 4 on histone H3: Intricacy of writing and reading a single epigenetic mark
Alexander J. Ruthenburg et al.
MOLECULAR CELL (2007)
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Helder I. Nakaya et al.
GENOME BIOLOGY (2007)
Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome
Michael Weber et al.
NATURE GENETICS (2007)
Surgical animal models of heart failure related to coronary heart disease
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CARDIOVASCULAR RESEARCH (2007)
Functions of Site-Specific Histone Acetylation and Deacetylation
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ANNUAL REVIEW OF BIOCHEMISTRY (2007)
Chromatin remodeling and cancer, part I: covalent histone modifications
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TRENDS IN MOLECULAR MEDICINE (2007)
Chromatin remodeling and cancer, part II: ATP-dependent chromatin remodeling
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Epigenetic changes in estrogen receptor beta gene in atherosclerotic cardiovascular tissues and in-vitro vascular senescence
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Histone acetyltransferase complexes: one size doesn't fit all
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Silibinin protects against isoproterenol-induced rat cardiac myocyte injury through mitochondrial pathway after up-regulation of SIRT1
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Altered cardiac myocyte Ca regulation in heart failure
Donald M. Bers
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Functional modulation of the transient outward current Ito by KCNE β-subunits and regional distribution in human non-failing and failing hearts
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Rubinstein-Taybi syndrome
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EUROPEAN JOURNAL OF HUMAN GENETICS (2006)
Histone deacetylase 7 maintains vascular integrity by repressing matrix metalloproteinase 10
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CELL (2006)
Alternative splicing of the first intron of the steroid receptor RNA activator (SRA) participates in the generation of coding and noncoding RNA isoforms in breast cancer cell lines
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DNA AND CELL BIOLOGY (2006)
Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases
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CELL (2006)
Epigenetics A Historical Overview
Robin Holliday
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Histone demethylation by a family of JmjC domain-containing proteins
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NATURE (2006)
Histone acetyltransferase activity of p300 is required for the promotion of left ventricular remodeling after myocardial infarction in adult mice in vivo
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CIRCULATION (2006)
Genomic instability and aging-like phenotype in the absence of mammalian SIRT6
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CELL (2006)
Identification of multiple distinct Snf2 subfamilies with conserved structural motifs
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NUCLEIC ACIDS RESEARCH (2006)
Identification of a novel non-coding RNA, MIAT, that confers risk of myocardial infarction
Nobuaki Ishii et al.
JOURNAL OF HUMAN GENETICS (2006)
Myocyte enhancer factor 2 acetylation by p300 enhances its DNA binding activity, transcriptional activity, and myogenic differentiation
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MOLECULAR AND CELLULAR BIOLOGY (2005)
Animal models of heart failure: What is new?
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ANNALS OF THORACIC SURGERY (2005)
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FJ Giordano
JOURNAL OF CLINICAL INVESTIGATION (2005)
MicroRNAs: Genomics, biogenesis, mechanism, and function
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CELL (2004)
Histone deacetylases 5 and 9 govern responsiveness of the heart to a subset of stress signals and play redundant roles in heart development
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MOLECULAR AND CELLULAR BIOLOGY (2004)
Mutations in a new member of the chromodomain gene family cause CHARGE syndrome
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NATURE GENETICS (2004)
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The cell-specific expression of endothelial nitric-oxide synthase - A role for DNA methylation
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Histone demethylation mediated by the nuclear arnine oxidase homolog LSD1
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CELL (2004)
Polybromo protein BAF180 functions in mammalian cardiac chamber maturation
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DNA methylation polymorphisms precede any histological sign of atherosclerosis in mice lacking apolipoprotein E
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JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
DNA methylation profiling of the human major histocompatibility complex: A pilot study for the Human Epigenome Project
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Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis
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CELL (2004)
Baf60c is essential for function of BAF chromatin remodelling complexes in heart development
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NATURE (2004)
The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote
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GENES & DEVELOPMENT (2004)
The steroid receptor RNA activator is the first functional RNA encoding a protein
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FEBS LETTERS (2004)
Essential function of p300 acetyltransferase activity in heart, lung and small intestine formation
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EMBO JOURNAL (2003)
Chromatin history: our view from the bridge
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NATURE REVIEWS MOLECULAR CELL BIOLOGY (2003)
Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
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NATURE (2003)
Cardiac p300 is involved in myocyte growth with decompensated heart failure
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MOLECULAR AND CELLULAR BIOLOGY (2003)
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JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Class II histone deacetylases act as signal-responsive repressors of cardiac hypertrophy
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CELL (2002)
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JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domain
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Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association
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GENES & DEVELOPMENT (2002)
Small amounts of α-myosin heavy chain isoform expression significantly increase power output of rat cardiac myocyte fragments
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CIRCULATION RESEARCH (2002)
Aurora-B associated protein phosphatases as negative regulators of kinase activation
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ONCOGENE (2002)
Enzymatic activity associated with class IIHDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR
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VASCULAR MEDICINE (2002)
Aurora-B phosphorylates histone H3 at serine28 with regard to the mitotic chromosome condensation
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JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
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CELL (2001)
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