Journal
KIDNEY INTERNATIONAL
Volume 93, Issue 2, Pages 303-305Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.kint.2017.09.031
Keywords
-
Categories
Funding
- National Natural Science Foundation of China [81370791, 81430017]
- China Scholarship Council
- National Institutes of Health of the United States [2R01DK058831, 1R01 DK087843]
- Department of Veterans Administration of the United States [5I01BX000319]
Ask authors/readers for more resources
Neutrophil extracellular traps, originally discovered as a mechanism to combat microbial infection, have recently been implicated in tissue damage including acute kidney injury. Raup-Konsavage et al. now present further insights to demonstrate a critical role of neutrophil peptidyl arginine deiminase-4 in the formation of neutrophil extracellular trap, inflammation, and tissue damage in ischemic acute kidney infection. Targeting peptidyl arginine deiminase-4 and/or neutrophil extracellular trap may offer a new therapeutic strategy for acute kidney infection.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available