4.6 Review

Depolymerized konjac glucomannan: preparation and application in health care

Journal

JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B
Volume 19, Issue 7, Pages 505-514

Publisher

ZHEJIANG UNIV
DOI: 10.1631/jzus.B1700310

Keywords

Konjac glucomannan; Depolymerized konjac glucomannan; Prebiotics; Immune response; Antioxidant

Funding

  1. National First-Class Discipline Program of Light Industry Technology and Engineering of China [LITE2018-18, LITE2018-11]
  2. Transformation Project for Major Scientific and Technological Achievements in Jiangsu Province [BA2015006]
  3. Industry-Academia Cooperation Innovation Fund Project of Jiangsu Province [BY2016022-19]
  4. National Key Technologies R&D Program of China [2012BAD33B06]

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Konjac glucomannan (KGM) is a water-soluble polysaccharide obtained from the roots and tubers of konjac plants. Recently, a degraded product of KGM, depolymerized KGM (DKGM), has attracted attention because of its low viscosity, improved hydrophily, and favorable physiological functions. In this review, we describe the preparation of DKGM and its prebiotic effects. Other health benefits of DKGM, covering antioxidant and immune activity, are also discussed, as well as its safety. DKGM could be a candidate for use as a tool for the treatment of various diseases, including intestinal flora imbalance, and oxidative- and immune-related disorders.

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