Journal
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
Volume 316, Issue 1, Pages 191-199Publisher
SPRINGER
DOI: 10.1007/s10967-018-5730-7
Keywords
Medium energy protons; Yttrium target; Zr-86 -> Y-86 generator; Ion exchange; ZR resin
Funding
- Russian Foundation for Fundamental Research [RFBR 15-5312372]
- JINR laboratories
- JINR Member States
- Czech scientific institutions
- Czech Republic-JINR representatives committee [03-2-11002010/2018]
- Health Research Agency of the Czech Republic
- Ministry of Education Youth and Sports of the Czech Republic
- EU [NV16-30544A, CAP-CZ. 02.1.01/0.0/0.0/15_003/0000464]
- National Research Council of Canada
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Utilization of (p, 4n) reaction channel for the production of medical radionuclides became very attractive with commercial availability of medium energy cyclotrons. Significantly higher yields and radionuclidic purity may open new perspectives for several novel and some of the radionuclides previously have not been considered due to production difficulties. In present work, we show the proof-of-principle study on the production of Y-86 for Positron Emission Tomography imaging via radionuclide generator Zr-86 -> Y-86. Production suitability of Zr-86 from natural yttrium target and radiochemical separation strategies were tested. In addition, two generator systems were proposed and evaluated.
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