Journal
JOURNAL OF PROTEOME RESEARCH
Volume 17, Issue 7, Pages 2552-2555Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.jproteome.8b00175
Keywords
bioinformatics; protein identification; search engines; de novo algorithms
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Funding
- Research Council of Norway
- Bergen Research Foundation
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Mass-spectrometry-based proteomics has become the standard approach for identifying and quantifying proteins. A vital step consists of analyzing experimentally generated mass spectra to identify the underlying peptide sequences for later mapping to the originating proteins. We here present the latest developments in SearchGUl, a common open-source interface for the most frequently used freely available proteomics search and de novo engines that has evolved into a central component in numerous bioinformatics workflows.
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