Journal
JOURNAL OF APPLIED BIOBEHAVIORAL RESEARCH
Volume 19, Issue 1, Pages 70-78Publisher
WILEY
DOI: 10.1111/jabr.12016
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Funding
- University of Miami Biopsychosocial Research Training in Immunology and AIDS Grant [5T32MH018917-24, 5 PO1 MH49548, SB04 1P30AI073961-02]
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The current study examines both linear and curvilinear relationships between oxytocin (OT) and depressive symptoms over time in ethnic minority women living with human immunodeficiency virus (HIV; WLWH). Participants were 70 WLWH aged 20-49 (86% African-American or Caribbean). OT was measured at baseline via enzyme-linked immunosorbent assay immunoassay procedures. Depressive symptoms were measured at both baseline and 10-week post-baseline via the Beck Depression Inventory-II (BDI-II). Multiple regression analyses revealed marginal linear and significant quadratic OT terms to be predictors of T2 BDI scores. Results indicate that to a point, OT may have salutary effects on depressive symptoms in ethnic minority WLWH. However, extremely high OT levels may be related to greater depressive symptoms.
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