Journal
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
Volume 44, Issue 2, Pages 452-458Publisher
SPRINGER/PLENUM PUBLISHERS
DOI: 10.1007/s10803-013-1888-6
Keywords
Autism; ASD; Epilepsy; EEG; Behavior
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Funding
- NCRR NIH HHS [T32 RR023254-05] Funding Source: Medline
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Autism spectrum disorders (ASD) are associated with an increased incidence of epilepsy and of epileptiform discharges on electroencephalograms. It is unknown whether epileptiform discharges correlate with symptoms of ASD. We completed a retrospective chart review of 101 patients with ASD who had overnight electroencephalograms. We looked for a relationship between epileptiform abnormalities and diagnosis, history of regression, communication skills, and other features associated with ASD. There was a higher incidence of epileptiform activity in children with stereotypies and aggressive behavior. The incidence of epileptiform abnormalities was significantly lower in Asperger's compared with more severe forms of autism. Results suggest that increasing severity of autistic symptoms may be associated with higher likelihood of epileptiform abnormalities. Whether treatment alters outcome is unknown.
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