Journal
MOVEMENT DISORDERS CLINICAL PRACTICE
Volume 1, Issue 1, Pages 67-69Publisher
WILEY
DOI: 10.1002/mdc3.12009
Keywords
Virchow-Robin; Parkinson's disease; clinical manifestations
Categories
Funding
- CIHR
- Michael J. Fox Foundation
- Pacific Alzheimer Research Foundation
- Canada Research Chairs program
- Ontario Problem Gambling Research Center
- Canadian Institutes of Health Research
- National Parkinson Foundation
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Dilated Virchow-Robin (VR) spaces are usually not considered to be symptomatic. We present three cases presenting with atypical clinical features, which otherwise had clinical/imaging findings consistent with idiopathic Parkinson's disease. In all cases, an isolated large VR space in the basal ganglia contralateral to the side of symptom onset was observed. We propose that the atypical features could be associated with the mass effect of a significantly enlarged VR space, which would cause a dysfunction downstream from the presynaptic nigrostriatal dopaminergic system.
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