Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 83, Issue 4, Pages 2263-2273Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.7b03150
Keywords
-
Categories
Funding
- National Natural Science Foundation of China [21176041, 21476041]
- innovation and technology team of Xinxiang [CXTD17004]
Ask authors/readers for more resources
An efficient and enantioselective alpha-benzoyloxylation of beta-keto esters has been achieved by phase-transfer catalysis. This simple catalytic procedure is applicable to a range of beta-keto esters with cinchona-derived N-oxide asymmetric phase-transfer catalysts and gives the corresponding products in good enantiopurity (up to 95% ee) and yield (up to 99%). This simple and effective oxyfunctionalization is a useful synthetic strategy for introducing an oxygen-containing functional group at the a position of beta-dicarbonyl compounds.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available