Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 83, Issue 16, Pages 9300-9304Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.8b01273
Keywords
-
Categories
Funding
- Ministry of Education, Culture, Sports, Science, and Technology (MEXT) of the Japanese Government [25288017, 26410124, 16H04144]
- Frontier Science Program of Graduate School of Science and Engineering, Chiba University
Ask authors/readers for more resources
Asymmetric Diels-Alder reaction was achieved under achiral conditions. Reaction of prochiral 2-methylfuran and N-phenylmaleimide in heptane or hexane solution at 80 degrees C efficiently gave a conglomerate crystal of exo-type Diels-Alder adduct selectively, and continuous suspension of the reaction mixture with glass beads promoted attrition-enhanced deracemization, leading to an optically active exo-adduct in 90% ee.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available