4.8 Article

Organocatalytic 1,3-dipolar cycloaddition reaction of α,β-unsaturated ketones with azides through iminium catalysis

Journal

GREEN CHEMISTRY
Volume 17, Issue 2, Pages 781-784

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4gc01929f

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Funding

  1. National University of Singapore [R143000532112, NRF-CRP7-2010-03]
  2. National Natural Science Foundation of China [NSFC 21272043]

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1,3-Dipolar cycloaddition reaction of alpha,beta-unsaturated ketones with azides through iminium catalysis has been developed. This method could furnish 1,4,5-trisubstituted 1,2,3-triazoles in good yields and high levels of regioselectivity.

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