Journal
RESEARCH IN DEVELOPMENTAL DISABILITIES
Volume 35, Issue 5, Pages 1072-1086Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.ridd.2014.01.032
Keywords
Fragile X syndrome; Autism spectrum disorder; Anxiety; Hyperactivity; Social avoidance; Psychiatric symptoms
Categories
Funding
- NICHD NIH HHS [U54 HD079125, R01 HD054764] Funding Source: Medline
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In the present study, we examined the profile of psychiatric symptoms in boys with fragile X syndrome (FXS) using a parent report instrument. In addition, by comparing boys with FXS to boys with nonsyndromic autism spectrum disorder (ASD) utilizing multiple matching strategies, we examined between-group differences in the types of psychiatric symptoms observed and in the strength of their concurrent associations. Across all matching strategies, symptoms of manic/hyperactive behaviors and general anxiety were more frequently reported for boys with FXS than for boys with nonsyndromic ASD. Results also indicated a positive association between social avoidance and general anxiety in FXS that was stronger than that observed in nonsyndromic ASD across all matching strategies. Theoretical and treatment implications are discussed. (C) 2014 Elsevier Ltd. All rights reserved.
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