Biogenic synthesis of CuO nanoparticles using Bauhinia tomentosa leaves extract: Characterization and its antibacterial application

An eco-friendly, biogenic synthesis of copper oxide nanoparticles (CuO NPs) using Bauhinia tomentosa leaf extract was reported. Characterization of the biosynthesized CuO NPs were performed by XRD, UV-Vis spectroscopy, TEM, EDAX and FTIR analysis. The formation of CuO NPs by bioreducing activity of B. tomentosa leaf extract was confirmed by the characteristic surface plasmon resonance peak observed at 384 nm in UV-visible spectroscopy analysis. The spherical shaped nanoscale CuO particles were observed in TEM analysis and EDX spectrum confirmed the presence of Cu in the synthesized NPs. In FTIR analysis, the chemical bonds corresponds to the phytochemicals responsible for bioreduction activity were identified. B. tomentosa leaf extract derived CuO NPs showed significant antibacterial action against E. coli (22 mm) and P. aeruginosa (17 mm). Results of this study revealed that B. tomentosa leaf extract was found to be a good bioreducing agent for CuO NPs synthesis. The antibacterial efficacy of the prepared CuO NPs can be utilized in biomedical applications. (C) 2018 Elsevier B.V. All rights reserved.