Journal
JOURNAL OF MOLECULAR BIOLOGY
Volume 430, Issue 21, Pages 3954-3968Publisher
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.jmb.2018.06.009
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Funding
- National Institutes of Health [R01-GM120604]
- National Science Foundation [DBI-1338415, DUE 1725940]
- US Department of Energy
- NIH-SEPA [R25OD023723]
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Modeling and visualization of the cellular mesoscale, bridging the nanometer scale of molecules to the micrometer scale of cells, is being studied by an integrative approach. Data from structural biology, proteomics, and microscopy are combined to simulate the molecular structure of living cells. These cellular landscapes are used as research tools for hypothesis generation and testing, and to present visual narratives of the cellular context of molecular biology for dissemination, education, and outreach. (C) 2018 Elsevier Ltd. All rights reserved.
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