Journal
JOURNAL OF INNATE IMMUNITY
Volume 10, Issue 5-6, Pages 414-421Publisher
KARGER
DOI: 10.1159/000489829
Keywords
Autoimmunity; Bacterial infection; Cancer; Coagulation; Extracellular traps; Inflammation
Categories
Ask authors/readers for more resources
Nearly 15 years after the first description of neutrophil extracellular traps (NETs), our knowledge concerning this structure has expanded considerably. Initially, NETs were considered solely an elaborate function of the innate immune system to combat invading microorganisms. Successively it became clear that NETs have farther-reaching capabilities. They are involved in a series of pathophysiological mechanisms ranging from inflammation to thrombosis where they fulfill essential functions when produced at the right site and the right time but can have a serious impact when generation or clearance of NETs is inadequately controlled. This review provides a concise overview on the far-reaching functions of NETs in health and disease. (c) 2018 S. Karger AG, Basel
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available