Green Synthesis, Antibacterial, and Antifungal Activities of 1,3,4-Oxadiazines

1,3,4-Oxadiazine derivatives were prepared via green and more sustainable procedure employing Grinding Chemistry. The green context of the procedure was evaluated by comparing its components with that of the conventional one. The antibacterial and antifungal activities of all the synthesized compounds were evaluated against some bacterial and fungal strains and showed promising results. The structures of the resulted compounds were identified and confirmed by elemental analysis and mass, H-1-NMR, and C-13-NMR spectroscopies.