Journal
JOURNAL OF HETEROCYCLIC CHEMISTRY
Volume 55, Issue 6, Pages 1489-1493Publisher
WILEY
DOI: 10.1002/jhet.3180
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Funding
- Research Fund of Ataturk University [2016/145]
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Syntheses of pyridazine and pyrrole analogues of 2-aminotetralin starting from 3-cyclohexene-1-carboxylic acid are reported. All syntheses involve the following key steps: Curtius rearrangement for amine functionality, inverse electron demand Diels-Alder addition with 1,2,4,5-tetrazine for pyridazine ring synthesis, and pyridazine-to-pyrrole ring contraction for pyrrole ring formation.
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