Journal
ARCHIVES OF CLINICAL INFECTIOUS DISEASES
Volume 9, Issue 3, Pages -Publisher
SHAHID BEHESHTI UNIV MEDICAL SCIENCES, FAC MED
DOI: 10.5812/archcid.17580
Keywords
Mucormycosis; Orbital Diseases; Middle Cerebral Arteries
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Introduction: Rhino-orbito-cerebral mucormycosis is a progressive angioinvasive fungal disorder which almost always complicates immunocompromised patients. Case presentation: We described a case of fulminant rhino-orbito-cerebral mucormycosis in a 65-year-old woman, who presented with progressive neurological deficits due to involvement of orbital apex and the central nervous system by local invasion of the left inferior frontal lobe, retrograde perineural spreading to the brain stem and middle cerebral arteries thrombosis. Discussion: Early diagnosis is mandatory in managing of this life-threatening disorder. Urgent surgical debridement associated with antifungal agents (amphotericin with posaconazole) is the mainstay of treatment.
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