Journal
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
Volume 33, Issue 5, Pages 998-1008Publisher
WILEY
DOI: 10.1111/jgh.14119
Keywords
Crohn's disease; endoscopic balloon dilation; resection; stricture; strictureplasty
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Crohn's disease (CD) is a chronic relapsing and remitting disease that can affect any segments of the gastrointestinal tract. More than 50% of patients with CD develop stricturing or penetrating complications within the first 10years after diagnosis. Strictures can lead to intestinal obstruction, which is a common indication for surgery. Despite significant advances in the understanding of the pathogenesis of intestinal fibrostenosis, imaging and therapeutic armamentarium of CD, the risk of intestinal surgery remained significantly high. Endoscopic balloon dilation is a promising first-line alternative to surgery as it is less invasive and could preserve intestinal length. In this review, we will evaluate the literature on the mechanism of intestinal fibrosis, emerging imaging techniques, and management strategies for CD associated strictures.
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