4.7 Article

Expression of mutant Asxl1 perturbs hematopoiesis and promotes susceptibility to leukemic transformation

Related references

Note: Only part of the references are listed.
Article Immunology

RUNX1 cooperates with FLT3-ITD to induce leukemia

Kira Behrens et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2017)

Article Multidisciplinary Sciences

ASXL2 is essential for haematopoiesis and acts as a haploinsufficient tumour suppressor in leukemia

Jean-Baptiste Micol et al.

NATURE COMMUNICATIONS (2017)

Article Cell Biology

Acute myeloid leukemia requires Hhex to enable PRC2-mediated epigenetic repression of Cdkn2a

Benjamin J. Shields et al.

GENES & DEVELOPMENT (2016)

Article Multidisciplinary Sciences

Propagation of trimethylated H3K27 regulated by polycomb protein EED is required for embryogenesis, hematopoietic maintenance, and tumor suppression

Takeshi Ueda et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Article Multidisciplinary Sciences

ASXL1 plays an important role in erythropoiesis

Hui Shi et al.

SCIENTIFIC REPORTS (2016)

Article Multidisciplinary Sciences

Combined Id1 and Id3 Deletion Leads to Severe Erythropoietic Disturbances

Qingshi Zhao et al.

PLOS ONE (2016)

Review Hematology

TGF-β signaling in the control of hematopoietic stem cells

Ulrika Blank et al.

BLOOD (2015)

Article Biochemistry & Molecular Biology

Minimal PU.1 reduction induces a preleukemic state and promotes development of acute myeloid leukemia

Britta Will et al.

NATURE MEDICINE (2015)

Article Multidisciplinary Sciences

Cancer-associated ASXL1 mutations may act as gain-of-function mutations of the ASXL1-BAP1 complex

Anand Balasubramani et al.

NATURE COMMUNICATIONS (2015)

Article Biochemistry & Molecular Biology

Age-related mutations associated with clonal hematopoietic expansion and malignancies

Mingchao Xie et al.

NATURE MEDICINE (2014)

Editorial Material Biochemistry & Molecular Biology

Targeting a new regulator of erythropoiesis to alleviate anemia

Robert F. Paulson

NATURE MEDICINE (2014)

Article Medicine, General & Internal

Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence

Giulio Genovese et al.

NEW ENGLAND JOURNAL OF MEDICINE (2014)

Article Medicine, General & Internal

Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes

Siddhartha Jaiswal et al.

NEW ENGLAND JOURNAL OF MEDICINE (2014)

Review Oncology

Animal models of leukemia: any closer to the real thing?

Guerry J. Cook et al.

CANCER AND METASTASIS REVIEWS (2013)

Review Biochemical Research Methods

Flow Cytometry Analysis of Murine Hematopoietic Stem Cells

Allison Mayle et al.

CYTOMETRY PART A (2013)

Article Biochemistry & Molecular Biology

TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS

Rachel Deplus et al.

EMBO JOURNAL (2013)

Article Medicine, Research & Experimental

Transcription factor RUNX1 promotes survival of acute myeloid leukemia cells

Susumu Goyama et al.

JOURNAL OF CLINICAL INVESTIGATION (2013)

Article Medicine, Research & Experimental

Myelodysplastic syndromes are induced by histone methylation-altering ASXL1 mutations

Daichi Inoue et al.

JOURNAL OF CLINICAL INVESTIGATION (2013)

Article Immunology

Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo

Omar Abdel-Wahab et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2013)

Article Biochemistry & Molecular Biology

Cholesterol efflux in megakaryocyte progenitors suppresses platelet production and thrombocytosis

Andrew J. Murphy et al.

NATURE MEDICINE (2013)

Article Biochemical Research Methods

A common ancestry for BAP1 and Uch37 regulators

Luis Sanchez-Pulido et al.

BIOINFORMATICS (2012)

Article Multidisciplinary Sciences

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

Jinghui Zhang et al.

NATURE (2012)

Article Multidisciplinary Sciences

Loss of the Tumor Suppressor BAP1 Causes Myeloid Transformation

Anwesha Dey et al.

SCIENCE (2012)

Article Oncology

Prognostic Significance of ASXL1 Mutations in Patients With Myelodysplastic Syndromes

Felicitas Thol et al.

JOURNAL OF CLINICAL ONCOLOGY (2011)

Article Medicine, General & Internal

Clinical Effect of Point Mutations in Myelodysplastic Syndromes

Rafael Bejar et al.

NEW ENGLAND JOURNAL OF MEDICINE (2011)

Article Multidisciplinary Sciences

Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB

Johanna C. Scheuermann et al.

NATURE (2010)

Article Biochemistry & Molecular Biology

Defining the Human Deubiquitinating Enzyme Interaction Landscape

Mathew E. Sowa et al.

Review Cell Biology

Molecular Pathways Mediating MDS/AML With Focus on AML1/RUNX1 Point Mutations

Yuka Harada et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2009)

Article Biochemistry & Molecular Biology

Differential Contribution of the Gata1 Gene Hematopoietic Enhancer to Erythroid Differentiation

Mikiko Suzuki et al.

MOLECULAR AND CELLULAR BIOLOGY (2009)

Article Multidisciplinary Sciences

Resolving the distinct stages in erythroid differentiation based on dynamic changes in membrane protein expression during erythropoiesis

Ke Chen et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Hematology

Runx1 is involved in primitive erythropoiesis in the mouse

Tomomasa Yokomizo et al.

BLOOD (2008)

Article Hematology

AML1 mutations induced MDS and MDS/AML in a mouse BMT model

Naoko Watanabe-Okochi et al.

BLOOD (2008)

Article Oncology

H3K79 Methylation Profiles Define Murine and Human MLL-AF4 Leukemias

Andrei V. Krivtsov et al.

CANCER CELL (2008)

Article Biochemistry & Molecular Biology

TLX1/HOX11-induced hematopoietic differentiation blockade

I. Riz et al.

ONCOGENE (2007)

Article Biochemistry & Molecular Biology

Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression

A Yokoyama et al.

MOLECULAR AND CELLULAR BIOLOGY (2004)

Article Immunology

Transgenic mice with hematopoietic and lymphoid specific expression of Cre

J de Boer et al.

EUROPEAN JOURNAL OF IMMUNOLOGY (2003)

Article Biochemistry & Molecular Biology

The transcriptional program of a human B cell line in response to Myc

M Schuhmacher et al.

NUCLEIC ACIDS RESEARCH (2001)