Related references
Note: Only part of the references are listed.EphA5 and EphA7 forward signaling enhances human hematopoietic stem and progenitor cell maintenance, migration, and adhesion via Rac 1 activation
Thao M. Nguyen et al.
EXPERIMENTAL HEMATOLOGY (2017)
miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells (vol 29, pg 214, 2016)
Eric R. Lechman et al.
CANCER CELL (2016)
Annexin A1 Is a Physiological Modulator of Neutrophil Maturation and Recirculation Acting on the CXCR4/CXCL12 Pathway
Isabel Daufenback Machado et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2016)
Treating cancer with selective CDK4/6 inhibitors
Ben O'Leary et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2016)
Developing structure-activity relationships from an HTS hit for inhibition of the Cks1-Skp2 protein-protein interaction
Rajinder Singh et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2015)
InteractiVenn: a web-based tool for the analysis of sets through Venn diagrams
Henry Heberle et al.
BMC BIOINFORMATICS (2015)
CLIPdb: a CLIP-seq database for protein-RNA interactions
Yu-Cheng T. Yang et al.
BMC GENOMICS (2015)
BET inhibitor resistance emerges from leukaemia stem cells
Chun Yew Fong et al.
NATURE (2015)
DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia
Chun-Wei Chen et al.
NATURE MEDICINE (2015)
Independent regulation of vertebral number and vertebral identity by microRNA-196 paralogs
Siew Fen Lisa Wong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Predicting effective microRNA target sites in mammalian mRNAs
Vikram Agarwal et al.
ELIFE (2015)
Track data hubs enable visualization of user-defined genome-wide annotations on the UCSC Genome Browser
Brian J. Raney et al.
BIOINFORMATICS (2014)
Requirement for CDK6 in MLL-rearranged acute myeloid leukemia
Theresa Placke et al.
BLOOD (2014)
miR-99a/100∼125b tricistrons regulate hematopoietic stem and progenitor cell homeostasis by shifting the balance between TGFβ and Wnt signaling
Stephan Emmrich et al.
GENES & DEVELOPMENT (2014)
Therapeutic antagonists of microRNAs deplete leukemia-initiating cell activity
Chinavenmeni S. Velu et al.
JOURNAL OF CLINICAL INVESTIGATION (2014)
Leukemic Stem Cell Frequency: A Strong Biomarker for Clinical Outcome in Acute Myeloid Leukemia
Monique Terwijn et al.
PLOS ONE (2014)
In Vivo RNAi Screening Identifies a Leukemia-Specific Dependence on Integrin Beta 3 Signaling
Peter G. Miller et al.
CANCER CELL (2013)
Pharmacological Inactivation of Skp2 SCF Ubiquitin Ligase Restricts Cancer Stem Cell Traits and Cancer Progression
Chia-Hsin Chan et al.
CELL (2013)
p27kip1 maintains a subset of leukemia stem cells in the quiescent state in murine MLL-leukemia
Jun Zhang et al.
MOLECULAR ONCOLOGY (2013)
TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions
Daehwan Kim et al.
GENOME BIOLOGY (2013)
Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia
Jolanta Grembecka et al.
NATURE CHEMICAL BIOLOGY (2012)
microRNA-9 regulates axon extension and branching by targeting Map1b in mouse cortical neurons
Federico Dajas-Bailador et al.
NATURE NEUROSCIENCE (2012)
Concise Review: Cancer Stem Cells and Minimal Residual Disease
Gabriel Ghiaur et al.
STEM CELLS (2012)
The sufficient minimal set of miRNA seed types
Daniel C. Ellwanger et al.
BIOINFORMATICS (2011)
The role of Skp2 in hematopoietic stem cell quiescence, pool size, and self-renewal
Jing Wang et al.
BLOOD (2011)
Selective Killing of Mixed Lineage Leukemia Cells by a Potent Small-Molecule DOT1L Inhibitor
Scott R. Daigle et al.
CANCER CELL (2011)
An Allosteric Inhibitor of the Human Cdc34 Ubiquitin-Conjugating Enzyme
Derek F. Ceccarelli et al.
CELL (2011)
The Cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genes
Dalibor Blazek et al.
GENES & DEVELOPMENT (2011)
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
Johannes Zuber et al.
NATURE (2011)
Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia
Mark A. Dawson et al.
NATURE (2011)
starBase: a database for exploring microRNA-mRNA interaction maps from Argonaute CLIP-Seq and Degradome-Seq data
Jian-Hua Yang et al.
NUCLEIC ACIDS RESEARCH (2011)
Capture of MicroRNA-Bound mRNAs Identifies the Tumor Suppressor miR-34a as a Regulator of Growth Factor Signaling
Ashish Lal et al.
PLOS GENETICS (2011)
Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet
Hartmut Doehner et al.
BLOOD (2010)
Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials
David Grimwade et al.
BLOOD (2010)
An Illegitimate microRNA Target Site within the 3′ UTR of MDM4 Affects Ovarian Cancer Progression and Chemosensitivity
Jessika Wynendaele et al.
CANCER RESEARCH (2010)
A Myc Network Accounts for Similarities between Embryonic Stem and Cancer Cell Transcription Programs
Jonghwan Kim et al.
CELL (2010)
Expression of miR-196b is not exclusively MLL-driven but is especially linked to activation of HOXA genes in pediatric acute lymphoblastic leukemia
Diana Schotte et al.
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL (2010)
Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation
Cole Trapnell et al.
NATURE BIOTECHNOLOGY (2010)
Genome-wide RNA-mediated interference screen identifies miR-19 targets in Notch-induced T-cell acute lymphoblastic leukaemia
Konstantinos J. Mavrakis et al.
NATURE CELL BIOLOGY (2010)
Tandem affinity purification of miRNA target mRNAs (TAP-Tar)
Nora Nonne et al.
NUCLEIC ACIDS RESEARCH (2010)
AltAnalyze and DomainGraph: analyzing and visualizing exon expression data
Dorothea Emig et al.
NUCLEIC ACIDS RESEARCH (2010)
Alternative splicing regulates mouse embryonic stem cell pluripotency and differentiation
Nathan Salomonis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
DIANA-mirPath: Integrating human and mouse microRNAs in pathways
G. L. Papadopoulos et al.
BIOINFORMATICS (2009)
TopHat: discovering splice junctions with RNA-Seq
Cole Trapnell et al.
BIOINFORMATICS (2009)
Regulation of mir-196b by MLL and its overexpression by MLL fusions contributes to immortalization
Relja Popovic et al.
BLOOD (2009)
Accurate microRNA target prediction correlates with protein repression levels
Manolis Maragkakis et al.
BMC BIOINFORMATICS (2009)
Disease candidate gene identification and prioritization using protein interaction networks
Jing Chen et al.
BMC BIOINFORMATICS (2009)
Hierarchical Maintenance of MLL Myeloid Leukemia Stem Cells Employs a Transcriptional Program Shared with Embryonic Rather Than Adult Stem Cells
Tim C. P. Somervaille et al.
CELL STEM CELL (2009)
The Ron receptor tyrosine kinase negatively regulates mammary gland branching morphogenesis
Sara E. Meyer et al.
DEVELOPMENTAL BIOLOGY (2009)
Dicer1 functions as a haploinsufficient tumor suppressor
Madhu S. Kumar et al.
GENES & DEVELOPMENT (2009)
ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays
Yifang Hu et al.
JOURNAL OF IMMUNOLOGICAL METHODS (2009)
DIANA-microT web server: elucidating microRNA functions through target prediction
M. Maragkakis et al.
NUCLEIC ACIDS RESEARCH (2009)
ToppGene Suite for gene list enrichment analysis and candidate gene prioritization
Jing Chen et al.
NUCLEIC ACIDS RESEARCH (2009)
MicroRNA-155 modulates the interleukin-1 signaling pathway in activated human monocyte-derived dendritic cells
Maurizio Ceppi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Alternative Splicing in the Differentiation of Human Embryonic Stem Cells into Cardiac Precursors
Nathan Salomonis et al.
PLOS COMPUTATIONAL BIOLOGY (2009)
Targeting the p27 E3 ligase SCFSkp2 results in p27-and Skp2-mediated cell-cycle arrest and activation of autophagy
Qing Chen et al.
BLOOD (2008)
MicroRNA expression profiling in relation to the genetic heterogeneity of acute myeloid leukemia
Mojca Jongen-Lavrencic et al.
BLOOD (2008)
Malignant transformation initiated by MII-AF9: Gene dosage and critical target cells
Weili Chen et al.
CANCER CELL (2008)
An extended transcriptional network for pluripotency of embryonic stem cells
Jonghwan Kim et al.
CELL (2008)
Module map of stem cell genes guides creation of epithelial cancer stem cells
David J. Wong et al.
CELL STEM CELL (2008)
MicroRNA expression in cytogenetically normal acute myeloid leukemia
Guido Marcucci et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
MLL protects CpG clusters from methylation within the Hoxa9 gene, maintaining transcript expression
Frank E. Erfurth et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Distinct microRNA expression profiles in acute myeloid leukemia with common translocations
Zejuan Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
The microRNA.org resource: targets and expression
Doron Betel et al.
NUCLEIC ACIDS RESEARCH (2008)
Widespread microRNA repression by Myc contributes to tumorigenesis
Tsung-Cheng Chang et al.
NATURE GENETICS (2008)
Improved human disease candidate gene prioritization using mouse phenotype
Jing Chen et al.
BMC BIOINFORMATICS (2007)
The role of site accessibility in microRNA target recognition
Michael Kertesz et al.
NATURE GENETICS (2007)
Impaired microRNA processing enhances cellular transformation and tumorigenesis
Madhu S. Kumar et al.
NATURE GENETICS (2007)
Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia
Tim C. P. Somervaille et al.
CANCER CELL (2006)
Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9
Andrei V. Krivtsov et al.
NATURE (2006)
Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies
Ting-Chao Chou
PHARMACOLOGICAL REVIEWS (2006)
A pathway in quiescent cells that controls p27(Kip1) stability, subcellular localization, and tumor suppression
A Besson et al.
GENES & DEVELOPMENT (2006)
A minicircuitry comprised of MicroRNA-223 and transcription factors NFI-A and C/EBPα regulates human granulopoiesis
F Fazi et al.
CELL (2005)
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
A Subramanian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
High stem cell frequency in acute myeloid leukemia at diagnosis predicts high minimal residual disease and poor survival
A van Rhenen et al.
CLINICAL CANCER RESEARCH (2005)
Mammalian polyhomeotic homologues Phc2 and Phc1 act in synergy to mediate polycomb repression of Hox genes
K Isono et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
MicroRNA expression profiles classify human cancers
J Lu et al.
NATURE (2005)
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
BP Lewis et al.
CELL (2005)
MicroRNA-directed cleavage of HOXB8 mRNA
S Yekta et al.
SCIENCE (2004)
Leukemic transformation of hematopoietic progenitors by MLL-GAS7 in the absence of Hoxa7 or Hoxa9
CW So et al.
BLOOD (2004)
Hoxa9 influences the phenotype but not the incidence of Mll-AF9 fusion gene leukemia
AR Kumar et al.
BLOOD (2004)
Embryonic lethality, decreased erythropoiesis, and defective octamer-dependent promoter activation in Oct-1-deficient mice
VEH Wang et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Chromosomal aberration of the 11q23 locus in acute leukemia and frequency of MLL gene translocation -: results in 378 adult patients
MC Cox et al.
AMERICAN JOURNAL OF CLINICAL PATHOLOGY (2004)
Skp2-dependent degradation of p27kip1 is essential for cell cycle progression
U Kossatz et al.
GENES & DEVELOPMENT (2004)
Prediction of mammalian microRNA targets
BP Lewis et al.
CELL (2003)
Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9
PM Ayton et al.
GENES & DEVELOPMENT (2003)
Identification of a gene expression signature associated with pediatric AML prognosis
T Yagi et al.
BLOOD (2003)
PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
VK Mootha et al.
NATURE GENETICS (2003)
LNA: a versatile tool for therapeutics and genomics
M Petersen et al.
TRENDS IN BIOTECHNOLOGY (2003)
Tumorigenesis -: RAF/RAS oncogenes and mismatch-repair status
H Rajagopalan et al.
NATURE (2002)
MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia
SA Armstrong et al.
NATURE GENETICS (2002)
Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53
J Parant et al.
NATURE GENETICS (2001)
An atlas on chromosomes in hematological malignancies. Example: 11q23 and MLL partners
JL Huret et al.
LEUKEMIA (2001)
A CDK-independent function of mammalian Cks1:: Targeting of SCFSkp2 to the CDK inhibitor p27Kip1
C Spruck et al.
MOLECULAR CELL (2001)
The cell-cycle regulatory protein Cks1 is required for SCFSkp2-mediated ubiquitinylation of p27
D Ganoth et al.
NATURE CELL BIOLOGY (2001)
Stem cell repopulation efficiency but not pool size is governed by p27kip1
T Cheng et al.
NATURE MEDICINE (2000)
Share Paper
