4.7 Article

Enzymatic glucose biosensor based on manganese dioxide nanoparticles decorated on graphene nanoribbons

Journal

JOURNAL OF ELECTROANALYTICAL CHEMISTRY
Volume 823, Issue -, Pages 610-616

Publisher

ELSEVIER SCIENCE SA
DOI: 10.1016/j.jelechem.2018.07.013

Keywords

Glucose biosensor; Graphene nanoribbons; Manganese dioxide; Screen printed electrodes

Funding

  1. Ministry of Education, Science and Technology, the Republic of Serbia [OI 172030]
  2. Magbiovin project (FP7-ERAChairs-Pilot Call-2013) [621375]
  3. Education of Modern Analytical and Bioanalytical Methods
  4. [CIII-CZ-0212-11-1718]

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A disposable glucose biosensor was prepared using nanoparticles of MnO2 decorated on graphene nanoribbons by surface modification with drop coating with the GOx and Nafion (R). Tested material was synthesized and characterized using several techniques. The biosensor could be operated under physiological conditions (0.1 M phosphate buffer, pH 7.4) and exhibited good reproducibility and stability. The linear range for the amperometric response of the biosensor at operating potential of +0.50 (versus Ag/AgCl) was from 0.1 to 1.4 mmol/l, with a detection limit of 0.05 mmol/l and high sensitivity of 56.32 mu A/mmol cm(2). Developed method was tested toward glucose quantification in real samples with satisfactory accuracy and precision.

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