Journal
EUROPEAN JOURNAL OF MEDICAL RESEARCH
Volume 19, Issue -, Pages -Publisher
BMC
DOI: 10.1186/2047-783X-19-33
Keywords
Laparoscopy; Caecum resection; Rats; Appendectomy; Stump closure; Laparoscopic procedures
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Background: Laparoscopic appendectomy (LA) has become one of the most common surgical procedures to date. To improve and standardize this technique further, cost-effective and reliable animal models are needed. Methods: In a pilot study, 30 Wistar rats underwent laparoscopic caecum resection (as rats do not have an appendix vermiformis), to optimize the instrumental and surgical parameters. A subsequent test study was performed in another 30 rats to compare three different techniques for caecum resection and bowel closure. Results: Bipolar coagulation led to an insufficiency of caecal stump closure in all operated rats (Group 1, n = 10). Endoloop ligation followed by bipolar coagulation and resection (Group 2, n = 10) or resection with a LigaSure (TM) device (Group 3, n = 10) resulted in sufficient caecal stump closure. Conclusions: We developed a LA model enabling us to compare three different caecum resection techniques in rats. In conclusion, only endoloop closure followed by bipolar coagulation proved to be a secure and cost-effective surgical approach.
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