Journal
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
Volume 55, Issue 6, Pages 3721-3726Publisher
ASSOC RESEARCH VISION OPHTHALMOLOGY INC
DOI: 10.1167/iovs.13-13674
Keywords
sclera; glaucoma; myopia; tangent modulus; noninvasive measurement
Categories
Funding
- Innovation and Technology Commission of the HKSAR, China [its/362/09]
Ask authors/readers for more resources
PURPOSE. We investigated an indentation technique to measure the scleral stiffness and tangent modulus of porcine eyes. METHODS. The scleral load-displacement responses were measured with a universal testing machine as a function of IOP in 15 porcine eyes ex vivo using a 5-mm diameter cylindrical flat-punch indenter. The scleral radius of curvature and scleral thickness were measured using a DSLR camera (Alpha 900) and a camera-mounted stereomicroscope (M205C), respectively. The relationships between scleral stiffness, tangent modulus, and IOP were examined. RESULTS. The mean local scleral radius of curvature and scleral thickness were 7.86 +/- 0.49 and 1.03 +/- 0.14 mm, respectively. The average scleral stiffness and scleral tangent modulus of porcine eyes were 0.13 +/- 0.02 N/mm and 0.20 +/- 0.04 MPa at 15 mm Hg, respectively. The scleral stiffness and scleral tangent modulus were correlated positively with IOP (scleral stiffness, 0.989 < r < 0.999, P < 0.001; scleral tangent modulus, 0.989 < r < 0.999, P < 0.001). CONCLUSIONS. The scleral indentation technique can provide a noninvasive approach to measure scleral stiffness and tangent modulus.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available