Journal
JOURNAL OF COLLOID AND INTERFACE SCIENCE
Volume 510, Issue -, Pages 292-301Publisher
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.jcis.2017.09.085
Keywords
Nanocomposites; Photothermal conversion; Photothermal therapy; Dual-modal imaging
Categories
Funding
- National Natural Science Foundation of P.R. China (NSFC) [51072026, 51573023]
- Development of Science and Technology Plan Projects of Jilin Province [20130206002GX, 20170101185JC]
Ask authors/readers for more resources
Multifunctional nanocomposites (NCs) incorporating magnetic, luminescent and photothermal conversion properties are endowed with potential application in many fields such as imaging, tumor detection, drug delivery and therapy. Here, multifunctional MWCNTs-NaGdF4:Yb3+, Er3+, Eu3+ NCs, which offer the potential for integrated bioimaging and photothermal therapy (PTT) were fabricated by a facile hydrothermal method. The resulting sample exhibits uniform morphology, bright dual-modal luminescence and intrinsic paramagnetic properties. Under near-infrared laser excitation, NCs have excellent photothermal conversion properties. In addition, the MTT assay in HeLa cells shows that the NCs have good biocompatibility. Moreover, the up-conversion luminescence (UCL) imaging, X-ray computed tomography (CT) imaging and PTT in vitro of NCs were investigated. The results indicate that NCs can be used for dual-modal imaging-guided diagnose and PTT of cancer cells. (C) 2017 Elsevier Inc. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available