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Soft Tissue and Uterine Leiomyosarcoma

Journal

JOURNAL OF CLINICAL ONCOLOGY
Volume 36, Issue 2, Pages 144-+

Publisher

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1200/JCO.2017.75.9845

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Funding

  1. Memorial Sloan Kettering Cancer Center Support Grant [P30-CA008748]
  2. Instituto de Salud Carlos III [PI16/01371]
  3. Catherine England Leiomyosarcoma Fund
  4. Jill Effect

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Leiomyosarcoma (LMS) is one of the most common subtypes of soft tissue sarcoma in adults and can occur in almost any part of the body. Uterine leiomyosarcoma is the most common subtype of uterine sarcoma. Increased awareness of this unique histology has allowed for the development of drugs that are specific to LMS and has begun to shed light on the similarities and possible unique aspects of soft tissue and uterine LMS. In this review, we summarize the current understanding of the epidemiology, diagnosis, genomics, and treatment options for LMS. (c) 2017 by American Society of Clinical Oncology

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