Journal
JOURNAL OF CLINICAL MICROBIOLOGY
Volume 56, Issue 4, Pages -Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.01934-17
Keywords
antimicrobial susceptibility testing; CLSI; evaluations
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Effective evaluations of antimicrobial susceptibility tests (ASTs) require robust study design. The Clinical and Laboratory Standards Institute (CLSI) Subcommittee on Antimicrobial Susceptibility Testing has recognized that many published studies reporting the performance of commercial ASTs (cASTs) suffer from major design and/ or analysis flaws, rendering the results difficult or impossible to interpret. This minireview outlines the current consensus of the Methods Development and Standardization Working Group of the CLSI Subcommittee on Antimicrobial Susceptibility Testing regarding best practices for systematic evaluation of the performance of an AST, including the analysis and presentation of essential data intended for publication.
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