Related references
Note: Only part of the references are listed.Phase I study of MRX34, a liposomal miR-34a mimic, administered twice weekly in patients with advanced solid tumors
Muhammad S. Beg et al.
INVESTIGATIONAL NEW DRUGS (2017)
Safety and activity of microRNA-loaded minicells in patients with recurrent malignant pleural mesothelioma: a first-in-man, phase 1, open-label, dose-escalation study
Nico van Zandwijk et al.
LANCET ONCOLOGY (2017)
In Vitro Dose Studies on Chitosan Nanoplexes for microRNA Delivery in Breast Cancer Cells
Kubra Kaban et al.
NUCLEIC ACID THERAPEUTICS (2017)
MiR-7 inhibits progression of hepatocarcinoma by targeting KLF-4 and promises a novel diagnostic biomarker
Weizhong Wu et al.
CANCER CELL INTERNATIONAL (2017)
The effects of chitosan/miR-200c nanoplexes on different stages of cancers in breast cancer cell lines
Kubra Kaban et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2016)
Cationic microRNA-delivering nanocarriers for efficient treatment of colon carcinoma in xenograft model
G. Liang et al.
GENE THERAPY (2016)
Modular degradable dendrimers enable small RNAs to extend survival in an aggressive liver cancer model
Kejin Zhou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Development of novel form of mimic microRNA for lung cancer therapy
Shinichiro Ohno et al.
CANCER RESEARCH (2015)
被撤回的出版物: MicroRNA-34a suppresses the breast cancer stem cell-like characteristics by downregulating Notch1 pathway (Retracted article. See APR, 2023)
Le Kang et al.
CANCER SCIENCE (2015)
Combinatorial Action of MicroRNAs let-7 and miR-34 Effectively Synergizes with Erlotinib to Suppress Non-small Cell Lung Cancer Cell Proliferation
Carlos Stahlhut et al.
CELL CYCLE (2015)
MicroRNA-15a induces cell apoptosis and inhibits metastasis by targeting BCL2L2 in non-small cell lung cancer
Tian Yang et al.
TUMOR BIOLOGY (2015)
Chitosan nanoparticle-mediated delivery of miRNA-34a decreases prostate tumor growth in the bone and its expression induces non-canonical autophagy
Sanchaika Gaur et al.
ONCOTARGET (2015)
Delivery of miR-34a by chitosan/PLGA nanoplexes for the anticancer treatment of multiple myeloma
Donato Cosco et al.
SCIENTIFIC REPORTS (2015)
Aptamer-Dendrimer Bioconjugates for Targeted Delivery of miR-34a Expressing Plasmid and Antitumor Effects in Non-Small Cell Lung Cancer Cells
Hongmei Wang et al.
PLOS ONE (2015)
Gadolinium-functionalized nanographene oxide for combined drug and microRNA delivery and magnetic resonance imaging
Hung-Wei Yang et al.
BIOMATERIALS (2014)
MiR-145, miR-133a and miR-133b inhibit proliferation, migration, invasion and cell cycle progression via targeting transcription factor Sp1 in gastric cancer
Tianzhu Qiu et al.
FEBS LETTERS (2014)
The systemic administration of an anti-miRNA oligonucleotide encapsulated pH-sensitive liposome results in reduced level of hepatic microRNA-122 in mice
Hiroto Hatakeyama et al.
JOURNAL OF CONTROLLED RELEASE (2014)
Designing a gold nanoparticle-based nanocarrier for microRNA transfection into the prostate and breast cancer cells
Asli Ekin et al.
JOURNAL OF GENE MEDICINE (2014)
Non-viral vectors for gene-based therapy
Hao Yin et al.
NATURE REVIEWS GENETICS (2014)
Protumorigenic effects of mir-145 loss in malignant pleural mesothelioma
M. Cioce et al.
ONCOGENE (2014)
Small RNA combination therapy for lung cancer
Wen Xue et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Therapeutic platforms based on gold nanoparticles and their covalent conjugates with drug molecules
Leonid Vigderman et al.
ADVANCED DRUG DELIVERY REVIEWS (2013)
Restoring expression of miR-16: a novel approach to therapy for malignant pleural mesothelioma
G. Reid et al.
ANNALS OF ONCOLOGY (2013)
Innovative Strategy for MicroRNA Delivery in Human Mesenchymal Stem Cells via Magnetic Nanoparticles
Anna Schade et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)
MiR-15a is underexpressed and inhibits the cell cycle by targeting CCNE1 in breast cancer
Qifeng Luo et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2013)
Enhanced hepatic delivery of siRNA and microRNA using oleic acid based lipid nanoparticle formulations
Xinmei Wang et al.
JOURNAL OF CONTROLLED RELEASE (2013)
The Janus Face of PAMAM Dendrimers Used to Potentially Cure Nonenzymatic Modifications of Biomacromolecules in Metabolic Disorders-A Critical Review of the Pros and Cons
Magdalena Labieniec-Watala et al.
MOLECULES (2013)
First microRNA mimic enters clinic
Aaron Bouchie
NATURE BIOTECHNOLOGY (2013)
Targeting Stat3 and Smad7 to restore TGF-β cytostatic regulation of tumor cells in vitro and in vivo
R. B. Luwor et al.
ONCOGENE (2013)
Therapeutic Delivery of MicroRNA-29b by Cationic Lipoplexes for Lung Cancer
Yun Wu et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2013)
miRNA-34 Prevents Cancer Initiation and Progression in a Therapeutically Resistant K-ras and p53-Induced Mouse Model of Lung Adenocarcinoma
Andrea L. Kasinski et al.
CANCER RESEARCH (2012)
Role of microRNAs in stem/progenitor cells and cardiovascular repair
Philipp Jakob et al.
CARDIOVASCULAR RESEARCH (2012)
A comparative study on nonviral genetic modifications in cord blood and bone marrow mesenchymal stem cells
Behnaz Bakhshandeh et al.
CYTOTECHNOLOGY (2012)
Cationic polyurethanes-short branch PEI-mediated delivery of Mir145 inhibited epithelial-mesenchymal transdifferentiation and cancer stem-like properties and in lung adenocarcinoma
Guang-Yuh Chiou et al.
JOURNAL OF CONTROLLED RELEASE (2012)
Lipid-based Nanoparticle Delivery of Pre-miR-107 Inhibits the Tumorigenicity of Head and Neck Squamous Cell Carcinoma
Longzhu Piao et al.
MOLECULAR THERAPY (2012)
Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing
Marco Gerlinger et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Inhibition of Neuroblastoma Tumor Growth by Targeted Delivery of MicroRNA-34a Using Anti-Disialoganglioside GD2 Coated Nanoparticles
Amanda Tivnan et al.
PLOS ONE (2012)
Smart Nanocarrier Based on PEGylated Hyaluronic Acid for Cancer Therapy
Ki Young Choi et al.
ACS NANO (2011)
The Metastasis-Associated microRNA miR-516a-3p Is a Novel Therapeutic Target for Inhibiting Peritoneal Dissemination of Human Scirrhous Gastric Cancer
Yoshifumi Takei et al.
CANCER RESEARCH (2011)
MicroRNA Replacement Therapy for miR-145 and miR-33a Is Efficacious in a Model of Colon Carcinoma
Ahmed Fawzy Ibrahim et al.
CANCER RESEARCH (2011)
microRNA-203 suppresses bladder cancer development by repressing bcl-w expression
Juanjie Bo et al.
FEBS JOURNAL (2011)
MicroRNA therapeutics
J. A. Broderick et al.
GENE THERAPY (2011)
Developing therapeutic microRNAs for cancer
A. G. Bader et al.
GENE THERAPY (2011)
Hsa-let-7g inhibits proliferation of hepatocellular carcinoma cells by downregulation of c-Myc and upregulation of p16INK4A
Fei-Fei Lan et al.
INTERNATIONAL JOURNAL OF CANCER (2011)
Upregulation of microRNA-451 increases cisplatin sensitivity of non-small cell lung cancer cell line (A549)
Hai-Bo Bian et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2011)
MicroRNA Delivery by Cationic Lipoplexes for Lung Cancer Therapy
Yun Wu et al.
MOLECULAR PHARMACEUTICS (2011)
MicroRNA-143 Regulates Human Osteosarcoma Metastasis by Regulating Matrix Metalloprotease-13 Expression
Mitsuhiko Osaki et al.
MOLECULAR THERAPY (2011)
Systemic Delivery of Tumor Suppressor microRNA Mimics Using a Neutral Lipid Emulsion Inhibits Lung Tumors in Mice
Phong Trang et al.
MOLECULAR THERAPY (2011)
The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44
Can Liu et al.
NATURE MEDICINE (2011)
miRBase: integrating microRNA annotation and deep-sequencing data
Ana Kozomara et al.
NUCLEIC ACIDS RESEARCH (2011)
Diabetes mellitus, a microRNA-related disease?
Claudiane Guay et al.
TRANSLATIONAL RESEARCH (2011)
MicroRNA-503 and the Extended MicroRNA-16 Family in Angiogenesis
Andrea Caporali et al.
TRENDS IN CARDIOVASCULAR MEDICINE (2011)
Synthetic Pre-miRNA-Based shRNA as Potent RNAi Triggers
Kazuya Terasawa et al.
JOURNAL OF NUCLEIC ACIDS (2011)
Chitosan-based formulations for delivery of DNA and siRNA
Shirui Mao et al.
ADVANCED DRUG DELIVERY REVIEWS (2010)
miR-199a-3p targets CD44 and reduces proliferation of CD44 positive hepatocellular carcinoma cell lines
Jon C. Henry et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
miR-126 inhibits non-small cell lung cancer cells proliferation by targeting EGFL7
Yanqin Sun et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
Involvement of miR-326 in chemotherapy resistance of breast cancer through modulating expression of multidrug resistance-associated protein 1
Zhongxing Liang et al.
BIOCHEMICAL PHARMACOLOGY (2010)
MiRNA-451 plays a role as tumor suppressor in human glioma cells
Yang Nan et al.
BRAIN RESEARCH (2010)
MicroRNA dysregulation in psychiatric disease
Brooke H. Miller et al.
BRAIN RESEARCH (2010)
hsa-miR-520h downregulates ABCG2 in pancreatic cancer cells to inhibit migration, invasion, and side populations
F. Wang et al.
BRITISH JOURNAL OF CANCER (2010)
Role of anti-oncomirs miR-143 and-145 in human colorectal tumors
Y. Akao et al.
CANCER GENE THERAPY (2010)
miR-126 functions as a tumour suppressor in human gastric cancer
Runhua Feng et al.
CANCER LETTERS (2010)
miRNA-96 Suppresses KRAS and Functions as a Tumor Suppressor Gene in Pancreatic Cancer
Shuangni Yu et al.
CANCER RESEARCH (2010)
The Promise of MicroRNA Replacement Therapy
Andreas G. Bader et al.
CANCER RESEARCH (2010)
Development of a Lung Cancer Therapeutic Based on the Tumor Suppressor MicroRNA-34
Jason F. Wiggins et al.
CANCER RESEARCH (2010)
CD44, a therapeutic target for metastasising tumours
Veronique Orian-Rousseau
EUROPEAN JOURNAL OF CANCER (2010)
PEGylated PAMAM dendrimers as a potential drug delivery carrier: in vitro and in vivo comparative evaluation of covalently conjugated drug and noncovalent drug inclusion complex
Yan-Yan Jiang et al.
JOURNAL OF DRUG TARGETING (2010)
miRNA-145 inhibits non-small cell lung cancer cell proliferation by targeting c-Myc
Zhe Chen et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2010)
MicroRNAs and Their Therapeutic Potential for Human Diseases: MicroRNAs, miR-143 and -145, Function as Anti-oncomirs and the Application of Chemically Modified miR-143 as an Anti-cancer Drug
Yukio Kitade et al.
JOURNAL OF PHARMACOLOGICAL SCIENCES (2010)
Systemic Delivery of Synthetic MicroRNA-16 Inhibits the Growth of Metastatic Prostate Tumors via Downregulation of Multiple Cell-cycle Genes
Fumitaka Takeshita et al.
MOLECULAR THERAPY (2010)
Nanoparticles Modified With Tumor-targeting scFv Deliver siRNA and miRNA for Cancer Therapy
Yunching Chen et al.
MOLECULAR THERAPY (2010)
MicroRNA-132-mediated loss of p120RasGAP activates the endothelium to facilitate pathological angiogenesis
Sudarshan Anand et al.
NATURE MEDICINE (2010)
Targeting microRNAs in cancer: rationale, strategies and challenges
Ramiro Garzon et al.
NATURE REVIEWS DRUG DISCOVERY (2010)
Regression of murine lung tumors by the let-7 microRNA
P. Trang et al.
ONCOGENE (2010)
MicroRNA-145 Targets YES and STAT1 in Colon Cancer Cells
Lea H. Gregersen et al.
PLOS ONE (2010)
MicroRNA Let-7a Inhibits Proliferation of Human Prostate Cancer Cells In Vitro and In Vivo by Targeting E2F2 and CCND2
Qingchuan Dong et al.
PLOS ONE (2010)
MiR-34a Attenuates Paclitaxel-Resistance of Hormone-Refractory Prostate Cancer PC3 Cells Through Direct and Indirect Mechanisms
Keitaro Kojima et al.
PROSTATE (2010)
MicroRNAs in Cancer
Ramiro Garzon et al.
ANNUAL REVIEW OF MEDICINE (2009)
miR-15a and miR-16 Are Implicated in Cell Cycle Regulation in a Rb-Dependent Manner and Are Frequently Deleted or Down-regulated in Non-Small Cell Lung Cancer
Nora Bandi et al.
CANCER RESEARCH (2009)
MicroRNA-101, Down-regulated in Hepatocellular Carcinoma, Promotes Apoptosis and Suppresses Tumorigenicity
Hang Su et al.
CANCER RESEARCH (2009)
Therapeutic microRNA Delivery Suppresses Tumorigenesis in a Murine Liver Cancer Model
Janaiah Kota et al.
CELL (2009)
MicroRNA control of muscle development and disease
Andrew H. Williams et al.
CURRENT OPINION IN CELL BIOLOGY (2009)
Controlled delivery of antisense oligonucleotides: a brief review of current strategies
Xiubo Zhao et al.
EXPERT OPINION ON DRUG DELIVERY (2009)
Most mammalian mRNAs are conserved targets of microRNAs
Robin C. Friedman et al.
GENOME RESEARCH (2009)
New class of microRNA targets containing simultaneous 5′-UTR and 3′-UTR interaction sites
Inhan Lee et al.
GENOME RESEARCH (2009)
MicroRNA-122, a Tumor Suppressor MicroRNA that Regulates Intrahepatic Metastasis of Hepatocellular Carcinoma
Wei-Chih Tsai et al.
HEPATOLOGY (2009)
let-7 MicroRNA Transfer in Pancreatic Cancer-Derived Cells Inhibits In Vitro Cell Proliferation but Fails to Alter Tumor Progression
Jerme Torrisani et al.
HUMAN GENE THERAPY (2009)
MicroRNA-122 Inhibits Tumorigenic Properties of Hepatocellular Carcinoma Cells and Sensitizes These Cells to Sorafenib
Shoumei Bai et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Causes and consequences of microRNA dysregulation in cancer
Carlo M. Croce
NATURE REVIEWS GENETICS (2009)
MicroRNA miR-34 Inhibits Human Pancreatic Cancer Tumor-Initiating Cells
Qing Ji et al.
PLOS ONE (2009)
p53 represses c-Myc through induction of the tumor suppressor miR-145
Mohit Sachdeva et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Role of MicroRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression in human cancer cells
Hua Zhu et al.
BIOCHEMICAL PHARMACOLOGY (2008)
Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres
Qing Ji et al.
BMC CANCER (2008)
miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells
Joachim Silber et al.
BMC MEDICINE (2008)
Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer
Minoru Toyota et al.
CANCER RESEARCH (2008)
Targeting of the Bmi-1 Oncogene/Stem Cell Renewal Factor by MicroRNA-128 Inhibits Glioma Proliferation and Self-Renewal
Jakub Godlewski et al.
CANCER RESEARCH (2008)
The let-7 microRNA reduces tumor growth in mouse models of lung cancer
Aurora Esquela-Kerscher et al.
CELL CYCLE (2008)
Cancer complexity slows quest for cure
Erika Check Hayden
NATURE (2008)
The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities
Desiree Bonci et al.
NATURE MEDICINE (2008)
Chemical Modification of siRNAs for In Vivo Use
Mark A. Behlke
OLIGONUCLEOTIDES (2008)
A microRNA DNA methylation signature for human cancer metastasis
Amaia Lujambio et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
microRNAs join the p53 network - another piece in the tumour-suppression puzzle
Lin He et al.
NATURE REVIEWS CANCER (2007)
Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells
Hiroshi Tazawa et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
RNAi therapeutics: Principles, prospects and challenges
Lars Aagaard et al.
ADVANCED DRUG DELIVERY REVIEWS (2007)
Therapeutic potential for microRNAs
Christine C. Esau et al.
ADVANCED DRUG DELIVERY REVIEWS (2007)
Expression profiling identifies microRNA signature in pancreatic cancer
Eun Jon Lee et al.
INTERNATIONAL JOURNAL OF CANCER (2007)
Instability of miRNA and cDNAs derivatives in RNA preparations
Valia Bravo et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Restoration of p53 function leads to tumour regression in vivo
Andrea Ventura et al.
NATURE (2007)
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
Wen Xue et al.
NATURE (2007)
Slicer and the Argonautes
Niraj H. Tolia et al.
NATURE CHEMICAL BIOLOGY (2007)
MicroRNA signatures in human cancers
George A. Calin et al.
NATURE REVIEWS CANCER (2006)
Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells
Yoshimasa Saito et al.
CANCER CELL (2006)
let-7 microRNA functions as a potential growth suppressor in human colon cancer cells
Yukihiro Akao et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2006)
Oncomirs - microRNAs with a role in cancer
A Esquela-Kerscher et al.
NATURE REVIEWS CANCER (2006)
A microRNA expression signature of human solid tumors defines cancer gene targets
S Volinia et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Adenovirus p53 gene therapy
JA Roth
EXPERT OPINION ON BIOLOGICAL THERAPY (2006)
Epigenetic therapy of cancer: past, present and future
CB Yoo et al.
NATURE REVIEWS DRUG DISCOVERY (2006)
Dendrimer biocompatibility and toxicity
R Duncan et al.
ADVANCED DRUG DELIVERY REVIEWS (2005)
MicroRNA gene expression deregulation in human breast cancer
MV Iorio et al.
CANCER RESEARCH (2005)
Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs
DV Morrissey et al.
NATURE BIOTECHNOLOGY (2005)
MicroRNA expression profiles classify human cancers
J Lu et al.
NATURE (2005)
Phylogenetic shadowing and computational identification of human microRNA genes
E Berezikov et al.
CELL (2005)
The role of branched polyesters and their modifications in the development of modern drug delivery vehicles
LA Dailey et al.
JOURNAL OF CONTROLLED RELEASE (2005)
2′-O-methyl-modified phosphorothioate antisense oligonucleotides have reduced non-specific effects in vitro
BH Yoo et al.
NUCLEIC ACIDS RESEARCH (2004)
The nuclear RNase III Drosha initiates microRNA processing
Y Lee et al.
NATURE (2003)
Low-molecular-weight polyethylenimine as a non-viral vector for DNA delivery: comparison of physicochemical properties, transfection efficiency and in vivo distribution with high-molecular-weight polyethylenimine
K Kunath et al.
JOURNAL OF CONTROLLED RELEASE (2003)
Cancer gene therapy: Fringe or cutting edge?
F McCormick
NATURE REVIEWS CANCER (2001)
Formulation of poly(D,L-lactic-co-glycolic acid) microparticles for rapid plasmid DNA delivery
AM Tinsley-Bown et al.
JOURNAL OF CONTROLLED RELEASE (2000)
Share Paper
